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This book is the culmination of an international effort to bring consistency and diagnostic efficiency to effusion cytology for the sake of patient care. The authors recognize special challenges in serous fluid cytopathology, such as reporting the presence of Mullerian epithelium in peritoneal fluids. What is an appropriate serous fluid volume to ensure adequacy? How should mesothelial proliferations be reported and is it appropriate to make an interpretation of malignant mesothelioma? How specific should a report be regarding the origin and subtyping of tumors found in serous fluids? What are the appropriate quality monitors for this specimen type? Special chapters on considerations for peritoneal washings, cytopreparatory techniques, mesothelioma and quality management are included to address these issues. The text contains literature reviews that elucidate existing evidence in support of current practices and recommendations. Expert opinions on where evidence was lacking, the most common practices were adopted by consensus, and where there was no commonality, are employed. Written by experts in the field, The International System for Serous Fluid Cytopathology serves as a collaborative effort between the International Academy of Cytology and the American Society for Cytopathology and calls upon participation of the international cytopathology and oncology communities to contribute to the development of a truly international system for reporting serous fluid cytology.
Pathology. --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine --- Medicine, Preventive --- Serous fluids --- Cytopathology. --- Serosal fluids --- Lymph
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in the human visceral pleura is the sole reliable criterion for the statement that it belongs to the ‘thick type’, while all observed animals have a ‘thin’ type VP. The mesothelium and underlying structures of the SM represent a highly permeable bidirectional membrane with signi?cant differences in the organ and region tra- port as a local phenomenon after horseradish peroxidase application. Stomata are constant features seen by SEM, but are occasional ?ndings observed by TEM over both sides of the diaphragm, lower intercostal spaces, anterior abdominal wall and greater omentum in untreated animals. Our data extend the location of stomata over the liver and broad ligament of the uterus. We strictly de?ned and nominated the main structures of the lymphatic regions as lymphatic units, stomata, and LL. Several different types of vascularization of omental and extraomental (medias- nal pleura and lesser pelvis) MS are observed after India ink application. Human and animal differences in their location, mesothelial covering, the vessel (blood and lymphatic) supply, free and connective tissue cells and their arrangement are discussed. The mesothelium and the BL changes start early in the gestation and continue throughout the postnatal period. Both cell types (?at and cubic) are already evident through prenatal life.
Anatomy. --- Embryology. --- Membranes (Biology). --- Serous fluids. --- Membranes --- Tissues --- Anatomy --- Serous Membrane --- Human Anatomy & Physiology --- Biology --- Zoology --- Health & Biological Sciences --- Cytology --- Animal Anatomy & Embryology --- Physiology --- Membranes (Biology) --- Serosal fluids --- Biological membranes --- Biomembranes --- Medicine. --- Human physiology. --- Biomedicine. --- Human Physiology. --- Lymph --- Biological interfaces --- Protoplasm --- Human biology --- Medical sciences --- Human body
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This revised and updated second edition contains multiple microscopic illustrations of all diagnostic entities and ancillary techniques, providing a comprehensive, authoritative guide to all aspects of serous effusions. It now includes the many new antibodies which have been tested since the previous edition, as well as a discussion on next-generation sequencing and molecularly targeted therapy. Section one covers diagnosis for benign and malignant effusions while section two discusses biology, therapy, and prognosis highlighting clinical approaches that may be of value. Serous Effusions provides an indispensable guide to all aspects of current practice for cytopathologists, cytotechnicians, pathologists, clinicians and researchers in training and practice.
Medicine. --- Oncology. --- Medical biochemistry. --- Pathology. --- Medicine & Public Health. --- Medical Biochemistry. --- Cancer --- Serous fluids --- Cytopathology. --- Serosal fluids --- Lymph --- Oncology . --- Biochemistry. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Disease (Pathology) --- Diseases --- Medicine --- Medicine, Preventive --- Tumors --- Composition --- Medical biochemistry --- Pathobiochemistry --- Pathological biochemistry --- Biochemistry --- Pathology
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Serous (peritoneal, pleural and pericardial) effusions are a frequently encountered clinical finding in everyday medical practice and one of the most common specimen types submitted for cytological evaluation. The correct diagnosis of effusions is critical for patient management, as well as for prognostication and yet many clinicians find diagnosis and treatment of cancer cells in effusions very challenging. Featuring multiple microscopic illustrations of all diagnostic entities and ancillary techniques (immunhistochemistry and molecular methods), this book provides a comprehensive, authoritative guide to all aspects of serous effusions, including etiology, morphology and ancillary diagnostic methods, as well as data related to therapeutic approaches and prognostication. Section One covers diagnosis for benign and malignant effusions including the etiological reasons for the accumulation of effusions that provides the reader with the full spectrum of differential diagnoses at this anatomic site. Section Two discusses biology, therapy and prognosis highlighting clinical approaches that may be of value to patients and the movement towards personalized medicine and targeted therapy. Written by experts in the field internationally, Serous Effusions will provide an indispensable guide to all aspects of current practice for cytopathologists, cytotechnicians, pathologists, clinicians and researchers in training and practice.
Cancer -- Cytopathology. --- Cancer --- Pleural Diseases --- Diseases --- Heart Diseases --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Body Fluids --- Medicine --- Respiratory Tract Diseases --- Cardiovascular Diseases --- Health Occupations --- Fluids and Secretions --- Disciplines and Occupations --- Anatomy --- Pericardial Effusion --- Pathology --- Diagnosis --- Neoplasms --- Ascitic Fluid --- Pleural Effusion --- Health & Biological Sciences --- Oncology --- Cytopathology --- Serous fluids. --- Membranes (Biology) --- Serosal fluids --- Biological membranes --- Biomembranes --- Medicine. --- Internal medicine. --- Oncology. --- Medical biochemistry. --- Pathology. --- Medicine & Public Health. --- Internal Medicine. --- Medical Biochemistry. --- Disease (Pathology) --- Medical sciences --- Medicine, Preventive --- Medical biochemistry --- Pathobiochemistry --- Pathological biochemistry --- Biochemistry --- Tumors --- Medicine, Internal --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Physicians --- Biological interfaces --- Protoplasm --- Lymph --- Oncology . --- Biochemistry. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Composition
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