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Sarcomas --- Sarcomen --- Sarcomes --- Soft tissue neoplasms --- Soft tissue tumors --- Tumeurs des tissus mous --- Tumoren van zachte weefsels --- Tumors [Soft tissue ] --- Sarcomas. --- SOFT TISSUE NEOPLASMS --- THERAPY --- DIAGNOSIS

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The main goal of the second edition of this book is to update the content on the rapidly growing field of lymphoscintigraphy, a radionuclide-based imaging procedure that provides information on the functional status of the lymphatic system. Although the technique was originally introduced to identify the cause of peripheral edema (i.e., blockage of the venous or lymphatic circulation), more recent and widespread applications include radioguided biopsy of the sentinel lymph node in patients with solid cancers. This procedure is crucial for the adequate planning of oncologic surgery in a growing number of cancers, most notably breast cancer, cutaneous melanoma, head and neck cancers, penile cancer, and cervical cancer. The book focuses on the latest advances in lymphoscintigraphy techniques, including both novel tracers recently approved for clinical use (especially in the field of sentinel lymph node mapping) and the expanding role of hybrid imaging with SPECT/CT – and in sentinel node detection using hybrid tracers (radiolabeled and fluorescent) for dual-signature guidance. Each chapter addresses the clinical application of lymphoscintigraphy in different anatomic areas or disease conditions. After an introductory section concerning the pathophysiology of the specific site/disease, the clinical relevance and impact of lymphoscintigraphy is demonstrated by a collection of richly illustrated teaching cases describing the lymphoscintigraphic patterns most commonly observed, as well as anatomic variants and technical pitfalls. Emphasis is placed on tomographic multimodality imaging. The book gathers contributions by experts in nuclear oncology, who have revised their chapters by updating the didactic material and adding clinical cases. Regarding sentinel lymph node biopsy in particular, a major distinction of this text is the incorporation of the staging guidelines of the American Joint Committee on Cancer (8th edition) into the didactic material.

Nuclear medicine. --- Oncology  . --- Surgery. --- Angiology. --- Pathology. --- Nuclear Medicine. --- Oncology. --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine --- Medicine, Preventive --- Surgery, Primitive --- Tumors --- Atomic medicine --- Radioisotopes in medicine --- Medical radiology --- Radioactive tracers --- Radioactivity --- Physiological effect --- Medicina nuclear --- Limfomes --- Nodes limfàtics --- Gammagrafia --- Malalties vasculars --- Autogammagrafia --- Cartografia isotòpica --- Cartografia (Medicina) --- Escintigrafia --- Escintil·lografia --- Escintil·lografia isotòpica --- Gammagrafia isotòpica --- Imatges per isòtops radioactius --- Imatges per radionúclids --- Radiografia per raigs gamma --- Diagnòstic per la imatge --- Diagnòstic radiològic --- Traçadors radioactius --- Fol·licles limfàtics --- Ganglis limfàtics --- Glàndules limfàtiques --- Nòduls limfàtics --- Sistema limfàtic --- Ganglis sentinelles --- Angiologia --- Malalties dels vasos sanguinis --- Aneurismes --- Insuficiència venosa --- Malaltia de Raynaud --- Malalties cerebrovasculars --- Vasculitis --- Cardiologia --- Limfoma --- Sarcomes germinoblàstics --- Sarcomes immunoblàstics --- Malalties del sistema limfàtic --- Malaltia de Hodgkin --- Isòtops radioactius en medicina --- Medicina atòmica --- Radiologia mèdica --- Cobaltoteràpia --- Isòtops radioactius en diagnòstic mèdic --- Isòtops radioactius en farmacologia

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This book addresses surgical management for recurrent soft tissue sarcomas (RSTS) based on a wealth of clinical cases. With aim to reduce recurrence rate, a surgical strategy of barrier resection plus repair reconstruction referring to natural barriers in human body for enhancing curative effect is presented in details. The first part introduces the general theory of surgical treatment for RSTS. The second part is a portfolio of clinical cases, showing the essential of the surgical strategy from hundreds of cases with tumour of different anatomical sites. Each case report is composed of detailed medical history, radiographic images and operational photos. It will help readers to make proper decisions on the basis of specific purposes. This book will be of benefit to oncologists, orthopaedic surgeons, general surgeon, plastic surgeons, and medical students.

Orthopedics. --- Surgical oncology. --- Surgical Orthopedics. --- Surgical Oncology. --- Cancer --- Oncologic surgery --- Oncological surgery --- Surgical oncology --- Orthopaedics --- Orthopedia --- Surgery --- Excision --- Treatment --- Soft tissue tumors --- Soft tissue neoplasms --- Tumors --- Treatment. --- Diagnosis. --- Sarcoma --- Recurrence. --- surgery --- Recrudescence --- Relapse --- Recrudescences --- Recurrences --- Relapses --- Cirurgia oncològica --- Metàstasi --- Càncer metastàtic --- Disseminació del càncer --- Metàstasi neoplàstica --- Tumors malignes secundaris --- Tumors metastàtics --- Tumors secundaris --- Cèl·lules canceroses --- Patologia --- Càncer --- Sarcomes --- Tumors del teixit connectiu --- Osteosarcoma --- Cirurgia del càncer --- Extirpació del càncer --- Oncologia quirúrgica --- Cirurgia --- Surgery.

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This thoroughly revised second edition complied in 2 books is an up-to-date overview of the current clinical advances in sarcoma and osteosarcoma. The new edition features detailed, in-depth discussions of microRNAs in osteosarcoma, historical perspectives of chemotherapy in the treatment of the disease, tumor targeted IL12 therapy and HER2 targeted therapy, the role of enhancer elements in regulating the prometastatic transcriptional program and more. Further, these essential volumes also includes new insights on Wnt signaling in osteosarcoma, the role of genomics, genetically modified T-cell therapy, liquid biopsy, oncolytic viruses, immunophenotyping, receptor tyrosine kinases and epigenetic-focused approaches for treatment of osteosarcoma metastases, as well as thoughts on the current standard of treatment for patients suffering from these cancers. In the years since the previous edition, there have been numerous new developments in this rapidly changing field; this new edition is both timely and urgently needed. When taken together these companion volumes, Current Clinical (Book 1) and Scientific (Book 2) Advances in Osteosarcoma, are a timely and urgently needed guide for laboratory investigators and clinical oncologists focused in sarcoma.

Osteosarcoma --- Osteosarcoma. --- Bone sarcoma --- Osteogenic sarcoma --- Osteoid sarcoma --- Osteolytic sarcoma --- Bones --- Sarcoma --- Cancer --- Cancer research. --- Medical microbiology. --- Cell biology. --- Pediatrics. --- Cancer Research. --- Medical Microbiology. --- Cell Biology. --- Paediatrics --- Pediatric medicine --- Medicine --- Children --- Cell biology --- Cellular biology --- Biology --- Cells --- Cancer research --- Diseases --- Health and hygiene --- Terapèutica --- Sarcomes --- Tumors del teixit connectiu --- Càncer --- Tumors --- Sarcoma osteogen --- Sarcoma osteoide --- Càncer d'ossos --- Sarcoma d'Ewing --- Teràpia --- Tractament (Medicina) --- Tractament de les malalties --- Medicina clínica --- Al·lopatia (Terapèutica) --- Antipirètics --- Cateterisme --- Dietoteràpia --- Fisioteràpia --- Fórmules magistrals --- Hormonoteràpia --- Immunoteràpia --- Injeccions intraarticulars --- Intubació --- Ioga --- Logopèdia --- Medicina alternativa --- Nutrició --- Quimioteràpia --- Radiologia intervencionista --- Terapèutica dental --- Terapèutica fisiològica --- Teràpia genètica --- Teràpia intravenosa --- Teràpia respiratòria --- Terapèutica veterinària --- Tractament pal·liatiu --- Ús terapèutic --- Cancer. --- Cytology. --- Cancer Biology. --- Cancers --- Carcinoma --- Malignancy (Cancer) --- Malignant tumors