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This fully updated edition provides selected mouse genetic techniques and their application in modeling varieties of human diseases. The chapters are mainly focused on the generation of different transgenic mice to accomplish the manipulation of genes of interest, tracing cell lineages, and modeling human diseases. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Mouse Genetics: Methods and Protocols, Second Edition delivers fundamental techniques and protocols to geneticists, molecular biologists, cell and developmental biologists, students, and postdoctoral fellows working in the various disciplines of genetics, developmental biology, mouse genetics, and modeling human diseases.

Ratolins transgènics --- Ratolins genèticament modificats --- Animals transgènics --- Ratolins --- Biology—Technique. --- Medicine—Research. --- Biology—Research. --- Zoology. --- Biological Techniques. --- Biomedical Research. --- Biology --- Natural history --- Animals --- Ratolins (Animals de laboratori) --- Genètica animal --- Genètica --- Genètica veterinària --- Enginyeria genètica animal --- Millorament selectiu d'animals --- Ratolins com a animals de laboratori --- Animals de laboratori