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This volume discusses popular methods to achieve different types of mutagenesis and forward/reverse genetics in Medicago truncatula. Several studies on genetic control of developmental and metabolic processes in this model legume are also described. The chapters in this book cover topics such as Targeting Induced Local Lesions IN Genomes (TILLING), Fast Neutron Bombardment (FNB), Tnt1 insertional mutagenesis, Virus-Induced Gene Silencing (VIGS), stable inactivation of microRNAs in roots, gene editing by CRISPR-Cas9, etc. This book also contains reviews on the specific use of these techniques in functional studies on the genetic control of seed, leaf, root, nodule, floral and fruit development in M. truncatula. Written for the highly successful Methods in Molecular Biology series format, chapters contain the kind of detailed description and implementation advice needed to promote success in the lab. Cutting-edge and thorough, Functional Genomics in Medicago truncatula: Methods and Protocols is a valuable resource for anyone interested in learning more about this developing field.

Plant genetics. --- Plant Genetics and Genomics. --- Plants --- Genetics --- Genòmica --- Genètica vegetal --- Fitogenètica --- Genètica de les plantes --- Genètica --- Genètica molecular vegetal --- Nombre de cromosomes de les plantes --- Millorament selectiu de plantes --- Genètica molecular --- Metagenòmica --- Nutrigenòmica --- Genomes

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This volume details protocols covering nearly all aspects of fungal genomics. New and updated chapters guide the reader through experimental genomics, biotechnologies, and the analysis and processing of data. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Fungal Genomics : Methods and Protocols, Second Edition aims to ensure successful results in the further study of this vital field.

Microbiology. --- Microbial biology --- Biology --- Microorganisms --- Fongs --- Genòmica --- Microbiologia --- Manuals de laboratori --- Tècniques de laboratori --- Biologia --- Bacteriologia --- Ecologia microbiana --- Genètica microbiana --- Microbiologia agrícola --- Microbiologia aquàtica --- Microbiologia dels sòls --- Microbiologia mèdica --- Microbiologia molecular --- Protozous --- Química microbiològica --- Virologia --- Microorganismes --- Microscòpia --- Genètica molecular --- Metagenòmica --- Nutrigenòmica --- Genomes --- Criptògames --- Ascomicets --- Basidiomicets --- Deuteromicets --- Llevats (Botànica) --- Mixomicets --- Bolets

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This book describes the development of genetic resources in amaranths, with a major focus on genomics, reverse, and forward genetics tools and strategies that have been developed for crop improvement. Amaranth is an ancient crop native to the New World. Interest in amaranths is being renewed, due to their adaptability, stress tolerance, and nutritional value. There are about 65 species in the genus, including Amaranthus caudatus L., A. cruentus L., and A. hypochondriacus L., which are primarily grown as protein-rich grains or pseudocereals. The genus also includes major noxious weeds (e.g., A. palmeri). The amaranths are within the Caryophyllales order and thus many species (e.g., A. tricolor) produce red (betacyanin) or yellow (betaxanthin) betalain pigments, which are chemically distinct from the anthocyanins responsible for red pigmentation in other plants. A. hypochondriacus, which shows disomic inheritance (2n = 32; n= 466 Mb), has been sequenced and annotated with 23,059 protein-coding genes. Additional members of the genus are now also been sequenced including weedy amaranths, other grain amaranths, and their putative progenitors.

Plant science. --- Botany. --- Genetics. --- Biotechnology. --- Agriculture. --- Plant Sciences. --- Genetics and Genomics. --- Farming --- Husbandry --- Industrial arts --- Life sciences --- Food supply --- Land use, Rural --- Chemical engineering --- Genetic engineering --- Biology --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology) --- Botanical science --- Floristic botany --- Phytobiology --- Phytography --- Phytology --- Plant biology --- Plant science --- Natural history --- Plants --- Genòmica --- Biotecnologia vegetal --- Biotecnologia dels conreus --- Biotecnologia de les plantes --- Biotecnologia agrícola --- Enginyeria genètica vegetal --- Obtencions vegetals (Dret) --- Genètica molecular --- Metagenòmica --- Nutrigenòmica --- Genomes --- Amarant --- Amaranthus --- Blet --- Marxant --- Velluter

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The world population is rapidly aging—it is estimated that by 1950, around 17% of the population will be elderly. In this context, aging involves several physiological, psychological and highly complex social processes that vary from one person to another. For a long time, medical care for older adults has focused on treating chronic, age-related diseases and their associated consequences. Recently, biomedical research brings a novel point of view to develop more effective interventions by targeting the aging process itself rather than separate conditions. There is a growing number of reports indicating that aging is driven by several interconnected mechanisms and biological components referred to as the molecular pillars of aging. Interfering with these mechanisms could help to treat, prevent, and understand the development of age-related diseases and associated syndromes. This book provides a clinical perspective and general update on biomedical and genetic research in aging, moving from an update in the molecular pillars of aging to a perspective of the most recent pharmacological, clinical, and diagnostic applications using genomic approaches and techniques. While this book focuses on the specifics of genetics and genomics, it also adopts a clinical perspective of geroscience, which seeks to understand the genetic, molecular and cellular mechanisms that make aging an important risk factor and, sometimes, a determining factor in the diseases and common chronic conditions of older people. Additionally, Clinical Genetics and Genomics of Aging is a significant contribution to support aging research, as it shows that collaboration across disciplines is relevant to progress in the field. As more and more people benefit from increased longevity, clinician and researchers will be empowered by this knowledge to contribute to the progress of aging research.

Human genetics. --- Human Genetics. --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology --- Aging --- Genetic aspects. --- Gene Expression Regulation --- genetics --- Expression Regulation, Gene --- Regulation, Gene Action --- Regulation, Gene Expression --- Gene Action Regulation --- Regulation of Gene Expression --- RNAi Therapeutics --- Gene Regulatory Networks --- Envelliment --- Genètica humana --- Genòmica --- Genètica molecular --- Metagenòmica --- Nutrigenòmica --- Genomes --- Antropologia física --- Biologia humana --- Genètica --- Herència humana --- Citogenètica humana --- Cromosomes humans --- Genètica de poblacions humanes --- Genètica mèdica --- Genètica molecular humana --- Psicologia genètica --- Genoma humà --- Senectut --- Biologia del desenvolupament --- Persones de mitjana edat --- Persones grans --- Gerontologia --- Longevitat --- Envelliment cerebral --- Factors d'edat en les malalties

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This book presents comprehensive information on genetics, genomics and breeding in Brassica oleracea, an agriculturally important species that includes popular vegetable crops such as cabbage, cauliflower, broccoli, Brussels sprouts, kale, collard greens, savoy, kohlrabi, and gai lan. The content spans whole genome sequencing, assembly and gene annotation for this global vegetable species, along with molecular mapping and cloning of genes, physical genome mapping and analyses of the structure and composition of centromeres in the B. oleracea genome. The book also elaborates on asymmetrical genome evolution and transposable elements in the B. oleracea describes gene family differentiation in comparison to other Brassica species and structural and functional genomic resources and data bases developed for B. oleracea. Useful discussions on the impact of genome sequencing on genetic improvement in the species are also included.

Plant breeding. --- Plant genetics. --- Agriculture. --- Plant Breeding/Biotechnology. --- Plant Genetics and Genomics. --- Farming --- Husbandry --- Industrial arts --- Life sciences --- Food supply --- Land use, Rural --- Plants --- Genetics --- Crops --- Agriculture --- Breeding --- Col --- Millorament selectiu de plantes --- Genòmica --- Genètica molecular --- Metagenòmica --- Nutrigenòmica --- Genomes --- Millora de plantes --- Millorament de conreus --- Millorament genètic de conreus --- Millorament genètic de les plantes --- Millorament genètic de plantes conreades --- Millorament vegetal --- Selecció artificial de les plantes --- Agricultura --- Millora de les espècies --- Hibridació vegetal --- Immunitat de les plantes --- Genètica vegetal --- Plantes transgèniques --- Cols --- Brassica oleracea --- Crucíferes