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This book is comprised of important reviews and cutting-edge original research papers concerning electrospun and electrosprayed formulations in drug delivery. Electrospinning and electrospraying have, in recent years, attracted increasing attention in the pharmaceutical sector, with research in the area advancing rapidly. It is now possible to prepare extremely complex systems using multi-fluid processes, and to increase production rates to an industrial scale. Electrospun formulations can be produced under GMP conditions and are in clinical trials. In this volume, we explore a range of topics around electrospinning and electrospraying in controlled drug delivery. Four reviews cover the exciting potential of cyclodextrin-containing fibers and the many potential biomedical applications of electrospun fibers. The use of electrospinning to prepare amorphous systems and improve the dissolution rate and solubility of poorly soluble active ingredients is addressed, and the possibilities of such materials in tissue engineering are comprehensively covered. The six original research papers cover the effect of molecular properties on API release from Eudragit-based electrospun fibers; ferulic acid solid dispersions; electrospun medicines to treat psoriasis; scale up of electrospinning and its use to produce low-dose tablets; transepithelial permeation of drugs released from electrospun fibers, and the possibilities for the synergistic chemophotothermal treatment of cancer.

tissue engineering --- cyclodextrin --- permeability --- poly (vinylpyrrolidone-co-vinyl acetate) --- crystalline --- antibacterial --- drug delivery --- homogenization --- capsaicin --- combination therapy --- high-shear mixing --- cyclodextrin-inclusion complexes --- amorphous --- high-speed electrospinning --- PMVE/MA --- aqueous solubility enhancement --- sieve analysis --- Raman mapping --- Eudragit --- nanofibers --- psoriasis --- PCL --- essential oils --- parameters --- antibiotics --- xanthan gum --- carvedilol --- amorphous composite --- coaxial electrospinning --- insoluble drug --- NIR-triggered drug release --- fast dissolution --- electrospinning --- oral drug delivery --- electrospun nanofibers --- poly-cyclodextrin --- TRPV1 --- gallic acid --- solid dispersion --- photothermal therapy --- drug release --- applications --- Drug delivery systems. --- Electrospinning. --- Nanoparticles. --- Nano-particles --- NPs (Nanoparticles) --- Nanoscale particles --- Nanostructured materials --- Particles --- Spinning --- Delivery systems, Drug --- Drug administration technology --- Drug delivery technology --- Drugs --- Pharmaceutical technology --- Delivery systems

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To mark the recent advances in nanomaterials and nanotechnology in biomedical imaging and cancer therapy, this book, entitled Application of Nanomaterials in Biomedical Imaging and Cancer Therapy includes a collection of important nanomaterial studies on medical imaging and therapy. The book covers recent works on hyperthermia, external beam radiotherapy, MRI-guided radiotherapy, immunotherapy, photothermal therapy, and photodynamic therapy, as well as medical imaging, including high-contrast and deep-tissue imaging, quantum sensing, super-resolution microscopy, and three-dimensional correlative light and electron microscopy. The significant research results and findings explored in this work are expected to help students, researchers and teachers working in the field of nanomaterials and nanotechnology in biomedical physics, to keep pace with the rapid development and the applications of nanomaterials in precise imaging and targeted therapy.

nanoparticles --- anisotropy --- plasmonic photothermal therapy --- surface plasmon resonance --- light scattering --- cancer treatment --- drug release --- microgels --- gold nanorods --- cancer therapy --- photothermal therapy --- photoacoustic imaging --- lung cancer --- EGFR-targeting --- nanoparticle --- cancer --- immunotherapy --- pH-responsive --- drug delivery --- application --- biomedical imaging --- correlative microscopy --- 3D CLEM --- volume imaging --- NIR-triggered --- photothermal agent --- deep tissue --- upconversion nanoparticles --- silica-coated UCNPs --- bio-imaging --- bio-application --- gold nanoparticles --- spiky nanoparticles --- phototheranostics --- colon cancer cells --- NIR triggering --- gold nanoparticle --- nanoparticle-enhanced radiotherapy --- MR-guided radiotherapy --- DNA damage --- Monte Carlo simulation --- dose enhancement --- magnetic field --- phototherapy --- photodynamic therapy --- Co-Fe ferrite nanoparticles --- magnetic hyperthermia --- specific loss power --- optimization --- alternative therapy --- n/a