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book (6)


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English (6)


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2021 (2)

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Book
Thyroid Hormone Nuclear Receptor : Methods and Protocols
Authors: ---
ISBN: 1493979027 1493979019 Year: 2018 Publisher: New York, NY : Springer New York : Imprint: Humana,

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Abstract

This volume aims to detail the advances in the field of Thyroid hormones (THs), namely T3 and T4, and their nuclear receptor TRs from a conceptual and methodological point of view. Chapters guide readers through a general introduction, TR's engineered mice, human genetics of TRs, control of the hypothalamus-pituitary-thyroid (HPT) axis, the relevance of the local THs production and metabolism and pathological consequences of TH/TR alterations. Non-mammalian models are also presented and discussed. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Thyroid Hormone Nuclear Receptor: Methods and Protocols aims to ensure successful results in the further study of this vital field.


Book
Surgery in Thyroid Eye Disease : A Conceptual Approach
Authors: ---
ISBN: 9813292202 9813292199 Year: 2020 Publisher: Singapore : Springer Singapore : Imprint: Springer,

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This surgical manual provides a step-by-step guide to various surgical procedures for patients with thyroid eye disease (TED). The key surgical steps are covered in detail, with intra-operative photographs. The manual addresses all aspects of TED, including the basic anatomy, surgical preparation, evaluation of imaging, and surgical procedures. TED is commonly encountered by oculoplastic surgeons and general ophthalmologists in their daily practice, and restoration of the normal appearance is vital to patients and their families. Surgical treatments for TED include basic oculoplastic surgery, complex eyelid surgery, strabismus surgery, orbital surgery, and aesthetic procedures. All of the contributing authors are eminent experts with vast experience in treating TED. High-resolution images will help readers understand the key surgical steps, and are combined with a minimal amount of text, reflecting the book’s focus on surgical technique. Offering a complete guide that contains all relevant surgical knowledge on TED, presented in a highly practice-oriented format, the book is a must-read for every surgeon whose work involves managing TED.


Book
Hormonal Pathology of the Uterus
Authors: ---
ISBN: 3030384748 303038473X Year: 2020 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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Hormonal influences, both natural and iatrogenic, are implicated in the most frequent health issues of women. Endometrial cancer is now the most common gynecologic cancer in the United States and the industrialized world. This cancer is strongly related to hormonal and metabolic factors. In addition, breast cancer treated with hormone therapy (Tamoxifen) may, in some cases, be associated with uterine pathology. Hormone therapy is used to improve the physiological effects and counteract abnormal and deleterious effects of “natural” hormonal activity. Millions of women receive hormone therapy at some point of their life: using oral contraceptives, reproductive technology, treatment for post-menopausal symptoms, among other uses. This book addresses a range of women’s health issues, from fertility to neoplasms, and their relationship with natural and iatrogenic hormonal effects. Chapters include clinical and pathological descriptions, theoretical and practical medical issues, and original studies and cases. Controversial issues in certain hormone therapies are presented with updated concepts based on clinical studies and novel statistical methods. The book will be useful for specialized and general physicians, oncologists, endocrinologists, researchers, medical students, and others in the field of women’s health. .


Book
Thyroid, obesity and metabolism : exploring links between thyroid function, obesity, metabolism and lifestyle
Author:
ISBN: 3030802671 3030802663 Year: 2021 Publisher: Cham, Switzerland : Springer,


Book
Neurosecretion: Secretory Mechanisms
Authors: ---
ISBN: 3030229890 3030229882 Year: 2020 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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Abstract

How do electrical activity and calcium signals in neurons influence the secretion of peptide hormones? This volume presents the current state of knowledge regarding the electrical, calcium signaling and synaptic properties of neuroendocrine systems from both vertebrate and invertebrate systems. The contributions span in vivo and in vitro studies that address: state‐dependent plasticity, relevance of firing patterns, membrane properties, calcium flux (including dynamic imaging and homeostasis), and molecular mechanisms of exocytosis, including from non-neuronal secretory cells. The chapters focus not only on research results but also on how experiments are conducted using state-of-the-art techniques, and how the resulting data are interpreted. While there are many books on the secretory properties of neurons, this is the first to focus on the distinctive secretory properties of neuroendocrine neurons. Accordingly, it offers an important text for undergraduate and graduate neuroscience students, and will also appeal to established scientists and postdoctoral fellows. This is the eighth volume in the Masterclass in Neuroendocrinology series* - now a co-publication between Springer Nature and the INF (International Neuroendocrine Federation). *Volumes 1-7 published by Wiley.


Book
70 Years of Levothyroxine
Author:
ISBN: 3030632776 3030632768 Year: 2021 Publisher: Springer Nature

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This open access book presents the history, pharmacokinetics and pharmacodynamics of levothyroxine, discussing its role in the thyroid pathophysiology of patients of various ages and during pregnancy. It also describes the influence of levothyroxine on heart, bone and in cancer. When it was first synthesized in 1949, levothyroxine represented a significant advance in the treatment of hypothyroidism, providing a safe and effective treatment option for millions of hypothyroid patients around the globe. This synthetic form of thyroxine is now one of the most prescribed drugs in the world. Levothyroxine was first introduced by Merck KGaA,Darmstadt, Germany, in 1972, and since then the company has remained actively engaged in research on this mainstay of hypothyroidism treatment. This book is intended for healthcare professionals.

Keywords

Endocrinology . --- Pharmacology. --- Endocrinology. --- Pharmacology/Toxicology. --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemicals --- Chemotherapy --- Drugs --- Pharmacy --- Internal medicine --- Hormones --- Physiological effect --- Hormones tiroides --- Medicaments --- Farmacologia --- Malalties de les glàndules endocrines --- Tiroide --- Endocrinologia clínica --- Endocrinopaties --- Malalties endocrines --- Trastorns hormonals --- Diabetis --- Endocrinologia pediàtrica --- Ginecologia endocrina --- Hiperparatiroïdisme --- Hipoglucèmia --- Malalties de l'ovari --- Malalties de les glàndules suprarenals --- Malalties del testicle --- Pubertat precoç --- Medicina --- Biofarmàcia --- Biotransformació (Metabolisme) --- Dermofarmacologia --- Desenvolupament de medicaments --- Estabilitat dels medicaments --- Farmacocinètica --- Farmacogenètica --- Farmacologia cardiovascular --- Farmacologia clínica --- Farmacologia dental --- Farmacologia geriàtrica --- Farmacologia molecular --- Farmacologia obstètrica --- Farmacologia ocular --- Farmacologia pediàtrica --- Farmacologia respiratòria --- Farmacologia renal --- Farmacologia veterinària --- Immunofarmacologia --- Isòtops radioactius en farmacologia --- Neurofarmacologia --- Psicofarmacologia --- Química farmacèutica --- Radiofàrmacs --- Resistència als medicaments --- Toxicologia --- Quimioteràpia --- Fàrmacs --- Medicines --- Farmacopees --- Compostos bioactius --- Accés als medicaments --- Afrodisíacs --- Agents antilipèmics --- Antidiabètics --- Botànica mèdica --- Conservació de medicaments --- Contraceptius --- Diürètics --- Envasament de medicaments --- Excipients --- Farmacognòsia --- Interaccions dels medicaments --- Medicaments antineoplàstics --- Medicaments cardiovasculars --- Medicaments congelats --- Medicaments liofilitzats --- Medicaments orfes --- Medicaments peptídics --- Medicaments respiratoris --- Microbiologia farmacèutica --- Psicofàrmacs --- Prescripció de medicaments --- Preu dels medicaments --- Relaxants musculars --- Administració de medicaments --- Farmàcia --- Matèria mèdica --- Validació (Medicaments) --- Fotofarmacologia --- Endocrinology --- Pharmacology/Toxicology --- Pharmacology --- Thyroid gland --- Hypothyroidism --- TSH --- Thyroid disorders --- Metabolism --- Open Access

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