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DNA ancestry companies generate revenues in the region of $1bn a year, and the company 23andMe is said to have sold 10 million DNA ancestry kits to date. Although evidently popular, the science behind how DNA ancestry tests work is mystifying and difficult for the general public to interpret and understand. In this accessible and engaging book, Sheldon Krimsky, a leading researcher, investigates the methods that different companies use for DNA ancestry testing. He also discusses what the tests are used for, from their application in criminal investigations to discovering missing relatives. With a lack of transparency from companies in sharing their data, absent validation of methods by independent scientists, and currently no agreed-upon standards of accuracy, this book also examines the ethical issues behind genetic genealogy testing, including concerns surrounding data privacy and security. It demystifies the art and science of DNA ancestry testing for the general reader.

Genetic genealogy --- DNA and genealogy --- DNA genealogy --- DNA in genealogy --- Genetics and genealogy --- Genetics in genealogy --- Genealogy --- 575.3 --- 575.3 Molecular genetics --- Molecular genetics --- Genetic genealogy.

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In The Genealogy of a Gene, Myles Jackson uses the story of the CCR5 gene to investigate the interrelationships among science, technology, and society. Mapping the varied "genealogy" of CCR5 -- intellectual property, natural selection, Big and Small Pharma, human diversity studies, personalized medicine, ancestry studies, and race and genomics -- Jackson links a myriad of diverse topics. The history of CCR5 from the 1990s to the present offers a vivid illustration of how intellectual property law has changed the conduct and content of scientific knowledge, and the social, political, and ethical implications of such a transformation. The CCR5 gene began as a small sequence of DNA, became a patented product of a corporation, and then, when it was found to be an AIDS virus co-receptor with a key role in the immune system, it became part of the biomedical research world -- and a potential moneymaker for the pharmaceutical industry. When it was further discovered that a mutation of the gene found in certain populations conferred near-immunity to the AIDS virus, questions about race and genetics arose. Jackson describes these developments in the context of larger issues, including the rise of "biocapitalism," the patentability of products of nature, the difference between U.S. and European patenting approaches, and the relevance of race and ethnicity to medical research.

AIDS (Disease) --- Genes. --- Genes --- Genetic genealogy. --- HIV (Viruses) --- AIDS-associated retrovirus --- AIDS virus --- ARV (Viruses) --- HTLV-III (Viruses) --- HTLV-III-LAV (Viruses) --- Human immunodeficiency viruses --- Human T-cell leukemia virus III --- Human T-cell lymphotropic virus III --- Human T-lymphotropic virus III --- IDAV (Viruses) --- Immunodeficiency-associated virus --- LAV (Viruses) --- LAV-HTLV-III (Viruses) --- Lymphadenopathy-associated virus --- T-lymphotrophic virus III, Human --- DNA and genealogy --- DNA genealogy --- DNA in genealogy --- Genetics and genealogy --- Genetics in genealogy --- Units of heredity --- Units of inheritance --- Acquired immune deficiency syndrome --- Acquired immunodeficiency syndrome --- Acquired immunological deficiency syndrome --- HTLV (Viruses) --- Virus-induced immunosuppression --- Genealogy --- Heredity --- Molecular genetics --- DNA --- HIV infections --- Immunological deficiency syndromes --- Receptors, CCR5 --- Patents as Topic. --- HIV Infections. --- Continental Population Groups --- Acquired Immunodeficiency Syndrome. --- genetics. --- Acquired Immune Deficiency Syndrome --- Acquired Immuno-Deficiency Syndrome --- AIDS --- Immunodeficiency Syndrome, Acquired --- Immunologic Deficiency Syndrome, Acquired --- Acquired Immuno Deficiency Syndrome --- Acquired Immuno-Deficiency Syndromes --- Acquired Immunodeficiency Syndromes --- Immuno-Deficiency Syndrome, Acquired --- Immuno-Deficiency Syndromes, Acquired --- Immunodeficiency Syndromes, Acquired --- Syndrome, Acquired Immuno-Deficiency --- Syndrome, Acquired Immunodeficiency --- Syndromes, Acquired Immuno-Deficiency --- Syndromes, Acquired Immunodeficiency --- CD4-Positive T-Lymphocytes --- HIV-1 --- AIDS Arteritis, Central Nervous System --- HIV Coinfection --- HTLV-III Infections --- HTLV-III-LAV Infections --- T-Lymphotropic Virus Type III Infections, Human --- Coinfection, HIV --- Coinfections, HIV --- HIV Coinfections --- HIV Infection --- HTLV III Infections --- HTLV III LAV Infections --- HTLV-III Infection --- HTLV-III-LAV Infection --- Infection, HIV --- Infection, HTLV-III --- Infection, HTLV-III-LAV --- Infections, HIV --- Infections, HTLV-III --- Infections, HTLV-III-LAV --- T Lymphotropic Virus Type III Infections, Human --- Trademarks --- Patents as Topics --- Trademark --- Human population genetics. --- Patents. --- SCIENCE, TECHNOLOGY & SOCIETY/History of Science --- BIOMEDICAL SCIENCES/General --- SOCIAL SCIENCES/Political Science/Public Policy & Law --- Human genetics --- Population genetics --- Philosophy of science