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Botulinum toxin. --- Botox (Trademark) --- Botulin --- Botulinismus toxin --- Botulinum neurotoxin --- Botulinus toxin --- Clostridium botulinum toxin --- Bacterial toxins --- Neurotoxic agents

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Botulinum toxin --- Neurotoxic agents --- Microbiological assay --- Microbiological assay. --- Toxicity testing --- Assay, Microbiological --- Microbial assay --- Biological assay --- Neuropoisons --- Neurotoxicants --- Neurotoxins --- Poisons --- Botox (Trademark) --- Botulin --- Botulinismus toxin --- Botulinum neurotoxin --- Botulinus toxin --- Clostridium botulinum toxin --- Bacterial toxins --- Toxines botuliniques --- Dosage microbiologique --- Toxicité

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Currently, there are tremendous advances being made in understanding the basic science of both the structure and function of botulinum neurotoxins. This knowledge is opening up opportunities in regard to both therapeutic uses and treatment and protection options for civil and bio-defense applications. This volume fully evaluates the status of neurotoxin research and exploitation, with a focus on clinical application. The book is a multi-authored collection of chapters written by the leading authorities responsible for the current scientific and clinical research that is advancing the understanding and exploitation of the neurotoxins, and is both up to date and authoritative.

Biology --- Health & Biological Sciences --- Biophysics --- Botulinum toxin. --- Botox (Trademark) --- Botulin --- Botulinismus toxin --- Botulinum neurotoxin --- Botulinus toxin --- Clostridium botulinum toxin --- Medicine. --- Molecular biology. --- Neurosciences. --- Pharmacology. --- Biomedicine. --- Molecular Medicine. --- Pharmacology/Toxicology. --- Biomedicine general. --- Bacterial toxins --- Neurotoxic agents --- Toxicology. --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Chemicals --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Pathology --- Physicians --- Toxicology --- Health Workforce --- Biomedicine, general. --- Drug effects --- Medical pharmacology --- Chemotherapy --- Drugs --- Pharmacy --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biomolecules --- Systems biology --- Physiological effect

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"Botulinum Toxin in Facial Rejuvenation, 2nd Edition, covers the entire range of the use of botulinum toxin for cosmetic purposes. Dr. Kate Coleman offers practical guidance for safe handling, selection and assessment of patients, potential complications and pitfalls, and aesthetic techniques, as well as comparative modalities and long-term management. This is an ideal resource for anyone who offers this sought-after procedure, including cosmetic surgeons, oculoplastic surgeons, dermatologists, physician's assistants, and registered nurses"--Publisher's description.

Botulinum toxin --- Facelift. --- Botulinum Toxins, Type A --- Face --- Therapeutic use. --- Faces --- Botox --- Botulinum A Toxin --- Botulinum Neurotoxin A --- Clostridium Botulinum Toxin Type A --- Clostridium botulinum A Toxin --- Meditoxin --- Neuronox --- Oculinum --- Onabotulinumtoxin A --- OnabotulinumtoxinA --- Vistabel --- Vistabex --- Botulinum Toxin Type A --- Neurotoxin A, Botulinum --- Toxin, Botulinum A --- Face lift --- Facelifts --- Rhytidectomy --- Rhytidoplasty --- Surgery, Plastic --- Surgery --- Cosmetic Techniques. --- Injections, Intramuscular. --- Intramuscular Injections --- Injection, Intramuscular --- Intramuscular Injection --- Intramuscular Absorption --- Cosmetic Technics --- Cosmetic Technic --- Cosmetic Technique --- Technic, Cosmetic --- Technics, Cosmetic --- Technique, Cosmetic --- Techniques, Cosmetic --- Dermal Fillers --- Dermatologic Surgical Procedures --- Botulinum Neurotoxin Type A --- Botulinum Toxin A --- Toxin A, Botulinum

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Botulinum neurotoxins are the most toxic natural substances and represent a major threat to the population when intentionally released in bioterrorist attacks. On the other hand, during the past two decades botulinum neurotoxins have become established as indispensable drugs for the treatment of a variety of severe neurological disorders. The need for efficient countermeasures as well as the expansion into additional fields of therapeutic application, call for comprehensive information on the botulinum neurotoxin molecules and their mode of action. Our knowledge of this subject has made great strides in recent years, setting the stage for the development of new botulinum neurotoxin-based molecules and novel applications. This book reviews the current status of basic botulinum neurotoxin research. The first part describes the genetic variability of the toxin-producing bacteria, and sheds light on each step from toxin ingestion to the abrogation of synaptic signaling including the intestinal passage and absorption, nerve cell binding and entry, and intracellular substrate cleavage. The remaining chapters detail progress made in detection methods for botulinum neurotoxins, the development of botulinum neurotoxin inhibitors, and strategies to refine the neurotoxins for further medicinal applications by means of recombinant technologies.

Botulinum toxin -- Therapeutic use. --- Botulinum Toxins -- therapeutic use. --- Botulinum toxin --- Botulinum Toxins --- Biological Science Disciplines --- Peripheral Nervous System Agents --- Metalloendopeptidases --- Natural Science Disciplines --- Bacterial Proteins --- Physiological Effects of Drugs --- Bacterial Toxins --- Metalloproteases --- Pharmacologic Actions --- Toxins, Biological --- Proteins --- Disciplines and Occupations --- Endopeptidases --- Amino Acids, Peptides, and Proteins --- Biological Factors --- Peptide Hydrolases --- Chemical Actions and Uses --- Chemicals and Drugs --- Hydrolases --- Enzymes --- Enzymes and Coenzymes --- Botulinum Toxins, Type A --- Pharmacology --- Neuromuscular Agents --- Health & Biological Sciences --- Human Anatomy & Physiology --- Medicine --- Animal Biochemistry --- Pharmacy, Therapeutics, & Pharmacology --- Neurology --- Therapeutic use --- Botulinum toxin. --- Neurotoxic agents. --- Neuropoisons --- Neurotoxicants --- Neurotoxins --- Botox (Trademark) --- Botulin --- Botulinismus toxin --- Botulinum neurotoxin --- Botulinus toxin --- Clostridium botulinum toxin --- Medicine. --- Neurosciences. --- Pharmacology. --- Biomedicine. --- Pharmacology/Toxicology. --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemicals --- Chemotherapy --- Drugs --- Pharmacy --- Neural sciences --- Neurological sciences --- Neuroscience --- Nervous system --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Pathology --- Physicians --- Physiological effect --- Poisons --- Bacterial toxins --- Neurotoxic agents --- Toxicology. --- Poisoning --- Toxicology --- Clostridium