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This book covers some well-known and some unexplored pathological aspects of management of peritoneal metastases and should be read by both surgeons and pathologists involved in the management of peritoneal surface malignancies. The evaluation of cytoreductive surgery specimens is explored for the prognostic information it can provide and recommendations for evaluation of such specimens are provided. The pathways and patterns of peritoneal dissemination and their clinical implications on the extent of surgery performed and other aspects of management are discussed for some common peritoneal tumours. The exploratory studies presented here provide a new perspective on the surgical resection of peritoneal metastases. Other important aspects of pathological evaluation like pathological response to chemotherapy, diagnosis and classification of rare peritoneal tumors have also been covered in different chapters. Keeping in sync with the progress in molecular oncology, the role of molecular oncology in the current and future management of peritoneal metastases is addressed for different tumors. .
Peritoneum --- Cancer. --- Oncology . --- Oncology. --- Tumors --- Peritoneu --- Metàstasi --- Oncologia --- Medicina --- Oncologia geriàtrica --- Oncologia pediàtrica --- Oncologia veterinària --- Càncer --- Infermeria oncològica --- Càncer metastàtic --- Disseminació del càncer --- Metàstasi neoplàstica --- Tumors malignes secundaris --- Tumors metastàtics --- Tumors secundaris --- Cèl·lules canceroses --- Patologia --- Abdomen --- Membranes (Biologia)
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This fully updated edition provides the most recent advances in cancer cell signaling knowledge combined with some discussion of the current challenges and prospects in cancer therapy. Beginning with an important section on cancer resistance, the main obstacle to effective cancer therapy, the book continues with chapters exploring state-of-the-art methods in epigenetic control of cancer, metastasis promotion, as well as a variety of new technologies in the study of cancer. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and timely, Cancer Cell Signaling: Methods and Protocols, Third Edition serves as an ideal guide to researchers seeking to overcome the challenges in the vital field of cancer cell signaling.
Cèl·lules canceroses --- Cèl·lules --- Patologia cel·lular --- Metàstasi --- Càncer --- Biomechanics. --- Cancer. --- Cancer Biology. --- Cancers --- Carcinoma --- Malignancy (Cancer) --- Malignant tumors --- Tumors --- Biological mechanics --- Mechanical properties of biological structures --- Biophysics --- Mechanics --- Contractility (Biology)
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This book addresses surgical management for recurrent soft tissue sarcomas (RSTS) based on a wealth of clinical cases. With aim to reduce recurrence rate, a surgical strategy of barrier resection plus repair reconstruction referring to natural barriers in human body for enhancing curative effect is presented in details. The first part introduces the general theory of surgical treatment for RSTS. The second part is a portfolio of clinical cases, showing the essential of the surgical strategy from hundreds of cases with tumour of different anatomical sites. Each case report is composed of detailed medical history, radiographic images and operational photos. It will help readers to make proper decisions on the basis of specific purposes. This book will be of benefit to oncologists, orthopaedic surgeons, general surgeon, plastic surgeons, and medical students.
Orthopedics. --- Surgical oncology. --- Surgical Orthopedics. --- Surgical Oncology. --- Cancer --- Oncologic surgery --- Oncological surgery --- Surgical oncology --- Orthopaedics --- Orthopedia --- Surgery --- Excision --- Treatment --- Soft tissue tumors --- Soft tissue neoplasms --- Tumors --- Treatment. --- Diagnosis. --- Sarcoma --- Recurrence. --- surgery --- Recrudescence --- Relapse --- Recrudescences --- Recurrences --- Relapses --- Cirurgia oncològica --- Metàstasi --- Càncer metastàtic --- Disseminació del càncer --- Metàstasi neoplàstica --- Tumors malignes secundaris --- Tumors metastàtics --- Tumors secundaris --- Cèl·lules canceroses --- Patologia --- Càncer --- Sarcomes --- Tumors del teixit connectiu --- Osteosarcoma --- Cirurgia del càncer --- Extirpació del càncer --- Oncologia quirúrgica --- Cirurgia --- Surgery.
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This volume of the series Rare Diseases of the Immune System presents detailed state of the art knowledge on the cellular primary immunodeficiencies; it includes extensive coverage of both basic science discoveries and the latest clinical advances in the field. The book is structured in accordance with the most recent classification of PIDs and also covers updates on the T cell immunological synapse. Readers will find comprehensive, in-depth descriptions of novel cellular PID genes and related clinical applications, mucosal T cells, and the various clinical phenotypes of cellular PIDs. Cellular Primary Immunodeficiencies will be of high value for immunologists, pediatricians, rheumatologists, oncologists, internists, and infectious disease specialists and will also be informative for MD, Master and PhD students.
Rheumatology. --- Immunology. --- Gene therapy. --- Gene Therapy. --- Therapy, Gene --- Genetic engineering --- Therapeutics --- Immunobiology --- Life sciences --- Serology --- Internal medicine --- Connective tissues --- Joints --- Diseases --- Immunodeficiency. --- Immune system --- Cytopathology. --- Immunological system --- Anatomy --- Immunology --- Immune deficiency --- Immunologic deficiency --- Immunological deficiency --- Immunity --- Immunosuppression --- Immunodeficiència --- Patologia cel·lular --- Sistema immunitari --- Sistema immunològic --- Anatomia --- Immunologia --- Cèl·lules immunocompetents --- Medul·la òssia --- Sistema limfàtic --- Citopatologia --- Cèl·lules --- Patologia --- Cèl·lules canceroses --- Citodiagnòstic --- Deficiència immunitària --- Immunitat --- Síndromes de deficiència immunitària --- Immunosupressió
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This new textbook on bacterial physiology is aimed at senior level students pursuing a one-semester course in the biology or microbiology curriculum. The text takes a balanced view of prokaryotic physiology, discussing both bioenergetics and bacterial metabolism in a way that establishes general principles and concepts and emphasizes throughout the information gained from model systems. The book also covers some experimental design issues, giving students an appreciation of the practical aspects and consequences of bacterial metabolism. It also stimulates students’ interests in future developments in the field by including discussions by five world-famous bacterial physiologists about future developments in the field.
Prokaryotes. --- Monera --- Procaryotae --- Procaryotes --- Prokaryonta --- Prokaryotae --- Prokaryotic protists --- Microorganisms --- Bacteriology. --- Microbiology. --- Biochemistry. --- Cytology. --- Biochemistry, general. --- Cell Biology. --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Medical sciences --- Microbial biology --- Microbiology --- Composition --- Cell biology. --- Cèl·lules --- Fisiologia cel·lular --- Fisiologia --- Motilitat cel·lular --- Biologia --- Reproducció --- Astròcits --- Blastoderma --- Cèl·lules eucariotes --- Cèl·lules canceroses --- Cèl·lules epitelials --- Cèl·lules germinals --- Cèl·lules hepàtiques --- Cèl·lules i teixits vegetals --- Cèl·lules mare --- Cèl·lules musculars --- Cèl·lules sanguínies --- Citoplasma --- Cromatina --- Fecundació --- Fibroblasts --- Histologia --- Irritabilitat --- Mort cel·lular --- Neurones --- Neurones motores --- Patologia cel·lular --- Protoplasts --- Protozous --- Ou (Biologia) --- Ultraestructura (Biologia) --- Citologia --- Clonatge --- Embriologia --- Protoplasma --- Regeneració (Biologia)
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"Cancer cell publishes reports of novel results in any area of cancer research, from molecular and cellular biology to clinical oncology."
Cancer cells --- Cancer --- Neoplasms --- Research --- Cellules cancéreuses --- Cancer cells. --- Cells --- Recherche --- Research. --- pathology. --- pathology --- Cell --- Benign Neoplasms --- Malignancy --- Neoplasia --- Neoplasm --- Neoplasms, Benign --- Tumors --- Benign Neoplasm --- Cancers --- Malignancies --- Neoplasias --- Neoplasm, Benign --- Tumor --- Cellules cancéreuses --- Pathology, Cellular --- Cell Biology --- Malignant Neoplasms --- Malignant Neoplasm --- Neoplasm, Malignant --- Neoplasms, Malignant --- Medical Oncology --- Cell Transformation, Neoplastic --- Neoplastic Cell Transformation --- Transformation, Neoplastic Cell --- Tumorigenic Transformation --- Neoplastic Transformation, Cell --- Cell Neoplastic Transformation --- Cell Neoplastic Transformations --- Cell Transformations, Neoplastic --- Neoplastic Cell Transformations --- Neoplastic Transformations, Cell --- Transformation, Cell Neoplastic --- Transformation, Tumorigenic --- Transformations, Cell Neoplastic --- Transformations, Neoplastic Cell --- Transformations, Tumorigenic --- Tumorigenic Transformations --- Cell Line, Transformed --- Oncology --- Neoplasms. --- Cèl·lules canceroses --- Càncer --- Investigació
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This book comprises select peer-reviewed proceedings of the medical challenge - C-NMC challenge: Classification of normal versus malignant cells in B-ALL white blood cancer microscopic images. The challenge was run as part of the IEEE International Symposium on Biomedical Imaging (IEEE ISBI) 2019 held at Venice, Italy in April 2019. Cell classification via image processing has recently gained interest from the point of view of building computer-assisted diagnostic tools for blood disorders such as leukaemia. In order to arrive at a conclusive decision on disease diagnosis and degree of progression, it is very important to identify malignant cells with high accuracy. Computer-assisted tools can be very helpful in automating the process of cell segmentation and identification because morphologically both cell types appear similar. This particular challenge was run on a curated data set of more than 14000 cell images of very high quality. More than 200 international teams participated in the challenge. This book covers various solutions using machine learning and deep learning approaches. The book will prove useful for academics, researchers, and professionals interested in building low-cost automated diagnostic tools for cancer diagnosis and treatment.
Cancer cells --- Cancer research. --- Biomedical engineering. --- Signal processing. --- Image processing. --- Speech processing systems. --- Optical data processing. --- Cancer Research. --- Biomedical Engineering and Bioengineering. --- Signal, Image and Speech Processing. --- Computer Imaging, Vision, Pattern Recognition and Graphics. --- Cancer research --- Optical computing --- Visual data processing --- Bionics --- Electronic data processing --- Integrated optics --- Photonics --- Computers --- Computational linguistics --- Electronic systems --- Information theory --- Modulation theory --- Oral communication --- Speech --- Telecommunication --- Singing voice synthesizers --- Pictorial data processing --- Picture processing --- Processing, Image --- Imaging systems --- Optical data processing --- Processing, Signal --- Information measurement --- Signal theory (Telecommunication) --- Clinical engineering --- Medical engineering --- Bioengineering --- Biophysics --- Engineering --- Medicine --- Optical equipment --- Cèl·lules canceroses --- Cèl·lules --- Patologia cel·lular --- Metàstasi --- Càncer --- Cancer --- Research.
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This book provides detailed information on the various types of cancer, etiology, effects, and challenges associated with current cancer treatment regimes. The present edition has been written to reflect recent developments, success rates and lacunae in herbal and modern cancer therapies. It also describes the use of several herbal formulations to boost patients’ immunity, in order to prevent or help them cope with several cancers. The book highlights several herbs/shrubs/trees that have been reported to possess anti-cancer properties, paving the way for in-depth research into the dose standardization and efficacy of plant-based bioactive molecules. It also focuses on the sustainable conservation of medicinal flora, so that, in future, novel biomolecules be extracted and made available for the treatment of various cancers. Given its highly relevant content, the book will benefit the entire cancer research community (students, scientists, pharmacists, herbalists and lecturers) at universities, research institutions and industry in the areas of oncology, herbal cancer therapy, biotechnology, drug discovery, pharmaceuticals, agriculture, and various disciplines of the biomedical sciences.
Cancer research. --- Oncology . --- Gene expression. --- Psychotherapy . --- Cancer Research. --- Oncology. --- Gene Expression. --- Psychotherapy. --- Psychagogy --- Therapy (Psychotherapy) --- Mental illness --- Clinical sociology --- Mental health counseling --- Genes --- Genetic regulation --- Tumors --- Cancer research --- Treatment --- Expression --- Cancer --- Alternative treatment. --- Alternative therapy --- Càncer --- Carcinoma --- Carcinosi --- Càncer d'ossos --- Càncer de cap --- Càncer de coll --- Càncer de bufeta --- Càncer de fetge --- Càncer de laringe --- Càncer de mama --- Càncer de pàncrees --- Càncer de pell --- Càncer de pròstata --- Càncer de pulmó --- Càncer de ronyó --- Càncer de tiroide --- Càncer d'ovari --- Càncer gastrointestinal --- Càncer ginecològic --- Càncer en els adolescents --- Càncer en els infants --- Medicaments antineoplàstics --- Melanoma --- Leucèmia --- Sarcoma --- Carcinògens --- Cèl·lules canceroses --- Cirurgia oncològica --- Infermeria oncològica --- Malalts de càncer --- Metàstasi --- Oncologia --- Research.
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This volume details key protocols for developing strategies in immunotherapy. Chapters guide the readers through protocols related to various DNA, RNA and protein methods to reprogram the immune system, immune cells, analyzing the effect of the reprogrammed cells, and key methods to consider and analyze patients enrolled in clinical trials with novel immunotherapy regimens. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cell Reprogramming for Immunotherapy: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Immune system. --- Immunotherapy. --- Therapeutic immunology --- Clinical immunology --- Therapeutics --- Immunological system --- Anatomy --- Immunology --- Immunoteràpia --- Sistema immunitari --- Cèl·lules --- Biologia --- Fisiologia --- Reproducció --- Astròcits --- Blastoderma --- Cèl·lules eucariotes --- Cèl·lules canceroses --- Cèl·lules epitelials --- Cèl·lules germinals --- Cèl·lules hepàtiques --- Cèl·lules i teixits vegetals --- Cèl·lules mare --- Cèl·lules musculars --- Cèl·lules sanguínies --- Citoplasma --- Cromatina --- Fecundació --- Fibroblasts --- Histologia --- Irritabilitat --- Mort cel·lular --- Neurones --- Neurones motores --- Patologia cel·lular --- Protoplasts --- Protozous --- Ou (Biologia) --- Ultraestructura (Biologia) --- Citologia --- Clonatge --- Embriologia --- Protoplasma --- Regeneració (Biologia) --- Sistema immunològic --- Anatomia --- Immunologia --- Cèl·lules immunocompetents --- Medul·la òssia --- Sistema limfàtic --- Terapèutica immunològica --- Immunologia clínica --- Terapèutica --- Adjuvants immunològics --- Seroteràpia --- Timosina --- Immunology. --- Cytology. --- Cell Biology. --- Cell biology --- Cellular biology --- Biology --- Cells --- Immunobiology --- Life sciences --- Serology
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This volume explores the techniques used to study human and animal pericytes. Chapters in this volume cover a range of topics such as pericyte dissociation from tissues, and analysis by immunohistochemistry and flow cytometry; avian chimaeras to investigate the embryonic development of cell lineage; pericyte purification by fluorescence activated cell sorting and ensuing culture; tissue turnover and regeneration; and the dynamic study of pericyte involvement in cancer dissemination, in situ, and in culture. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Pericytes: Methods and Protocols is a valuable resource that helps researchers define the biologic identity, functions, and potentials of a cell lineage of increasing interest and therapeutic significance. .
Cèl·lules --- Sistema cardiovascular --- Aparell cardiovascular --- Aparell circulatori --- Sistema circulatori --- Sistema vascular --- Artèries --- Cor --- Sistema vasomotor --- Vasos sanguinis --- Circulació sanguínia --- Biologia --- Fisiologia --- Reproducció --- Astròcits --- Blastoderma --- Cèl·lules eucariotes --- Cèl·lules canceroses --- Cèl·lules epitelials --- Cèl·lules germinals --- Cèl·lules hepàtiques --- Cèl·lules i teixits vegetals --- Cèl·lules mare --- Cèl·lules musculars --- Cèl·lules sanguínies --- Citoplasma --- Cromatina --- Fecundació --- Fibroblasts --- Histologia --- Irritabilitat --- Mort cel·lular --- Neurones --- Neurones motores --- Patologia cel·lular --- Protoplasts --- Protozous --- Ou (Biologia) --- Ultraestructura (Biologia) --- Citologia --- Clonatge --- Embriologia --- Protoplasma --- Regeneració (Biologia) --- Cytology. --- Cell Biology. --- Cell biology --- Cellular biology --- Biology --- Cells --- Biologia cel·lular --- Citogenètica --- Citoquímica --- Migració cel·lular --- Cèl·lules animals
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