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Pathology of Peritoneal Metastases : The Unchartered Fields
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ISBN: 9811537739 9811537720 Year: 2020 Publisher: Singapore : Springer Singapore : Imprint: Springer,

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This book covers some well-known and some unexplored pathological aspects of management of peritoneal metastases and should be read by both surgeons and pathologists involved in the management of peritoneal surface malignancies. The evaluation of cytoreductive surgery specimens is explored for the prognostic information it can provide and recommendations for evaluation of such specimens are provided. The pathways and patterns of peritoneal dissemination and their clinical implications on the extent of surgery performed and other aspects of management are discussed for some common peritoneal tumours. The exploratory studies presented here provide a new perspective on the surgical resection of peritoneal metastases. Other important aspects of pathological evaluation like pathological response to chemotherapy, diagnosis and classification of rare peritoneal tumors have also been covered in different chapters. Keeping in sync with the progress in molecular oncology, the role of molecular oncology in the current and future management of peritoneal metastases is addressed for different tumors. .


Book
Cancer Cell Signaling : Methods and Protocols
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ISBN: 1071607596 1071607588 Year: 2021 Publisher: New York, NY : Springer US : Imprint: Humana,

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This fully updated edition provides the most recent advances in cancer cell signaling knowledge combined with some discussion of the current challenges and prospects in cancer therapy. Beginning with an important section on cancer resistance, the main obstacle to effective cancer therapy, the book continues with chapters exploring state-of-the-art methods in epigenetic control of cancer, metastasis promotion, as well as a variety of new technologies in the study of cancer. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and timely, Cancer Cell Signaling: Methods and Protocols, Third Edition serves as an ideal guide to researchers seeking to overcome the challenges in the vital field of cancer cell signaling.


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Surgery for Recurrent Soft Tissue Sarcoma : Barrier Resection and Reconstruction
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ISBN: 9811512329 9811512310 Year: 2020 Publisher: Singapore : Springer Singapore : Imprint: Springer,

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This book addresses surgical management for recurrent soft tissue sarcomas (RSTS) based on a wealth of clinical cases. With aim to reduce recurrence rate, a surgical strategy of barrier resection plus repair reconstruction referring to natural barriers in human body for enhancing curative effect is presented in details. The first part introduces the general theory of surgical treatment for RSTS. The second part is a portfolio of clinical cases, showing the essential of the surgical strategy from hundreds of cases with tumour of different anatomical sites. Each case report is composed of detailed medical history, radiographic images and operational photos. It will help readers to make proper decisions on the basis of specific purposes. This book will be of benefit to oncologists, orthopaedic surgeons, general surgeon, plastic surgeons, and medical students.


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Cellular primary immunodeficiencies
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ISBN: 3030701077 3030701069 Year: 2021 Publisher: Cham, Switzerland : Springer,

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This volume of the series Rare Diseases of the Immune System presents detailed state of the art knowledge on the cellular primary immunodeficiencies; it includes extensive coverage of both basic science discoveries and the latest clinical advances in the field. The book is structured in accordance with the most recent classification of PIDs and also covers updates on the T cell immunological synapse. Readers will find comprehensive, in-depth descriptions of novel cellular PID genes and related clinical applications, mucosal T cells, and the various clinical phenotypes of cellular PIDs. Cellular Primary Immunodeficiencies will be of high value for immunologists, pediatricians, rheumatologists, oncologists, internists, and infectious disease specialists and will also be informative for MD, Master and PhD students.

Structural and Functional Relationships in Prokaryotes
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ISBN: 0387271252 0387207082 Year: 2005 Publisher: New York, NY : Springer New York : Imprint: Springer,

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This new textbook on bacterial physiology is aimed at senior level students pursuing a one-semester course in the biology or microbiology curriculum. The text takes a balanced view of prokaryotic physiology, discussing both bioenergetics and bacterial metabolism in a way that establishes general principles and concepts and emphasizes throughout the information gained from model systems. The book also covers some experimental design issues, giving students an appreciation of the practical aspects and consequences of bacterial metabolism. It also stimulates students’ interests in future developments in the field by including discussions by five world-famous bacterial physiologists about future developments in the field.


Periodical
Cancer cell.
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ISSN: 18783686 15356108 Year: 2002 Publisher: Cambridge, Mass. : Cell Press,


Book
ISBI 2019 C-NMC Challenge: Classification in Cancer Cell Imaging : Select Proceedings
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ISBN: 9811507988 981150797X Year: 2019 Publisher: Singapore : Springer Singapore : Imprint: Springer,

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This book comprises select peer-reviewed proceedings of the medical challenge - C-NMC challenge: Classification of normal versus malignant cells in B-ALL white blood cancer microscopic images. The challenge was run as part of the IEEE International Symposium on Biomedical Imaging (IEEE ISBI) 2019 held at Venice, Italy in April 2019. Cell classification via image processing has recently gained interest from the point of view of building computer-assisted diagnostic tools for blood disorders such as leukaemia. In order to arrive at a conclusive decision on disease diagnosis and degree of progression, it is very important to identify malignant cells with high accuracy. Computer-assisted tools can be very helpful in automating the process of cell segmentation and identification because morphologically both cell types appear similar. This particular challenge was run on a curated data set of more than 14000 cell images of very high quality. More than 200 international teams participated in the challenge. This book covers various solutions using machine learning and deep learning approaches. The book will prove useful for academics, researchers, and professionals interested in building low-cost automated diagnostic tools for cancer diagnosis and treatment.


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Herbs for Cancer Treatment
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ISBN: 9813291478 981329146X Year: 2019 Publisher: Singapore : Springer Singapore : Imprint: Springer,

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This book provides detailed information on the various types of cancer, etiology, effects, and challenges associated with current cancer treatment regimes. The present edition has been written to reflect recent developments, success rates and lacunae in herbal and modern cancer therapies. It also describes the use of several herbal formulations to boost patients’ immunity, in order to prevent or help them cope with several cancers. The book highlights several herbs/shrubs/trees that have been reported to possess anti-cancer properties, paving the way for in-depth research into the dose standardization and efficacy of plant-based bioactive molecules. It also focuses on the sustainable conservation of medicinal flora, so that, in future, novel biomolecules be extracted and made available for the treatment of various cancers. Given its highly relevant content, the book will benefit the entire cancer research community (students, scientists, pharmacists, herbalists and lecturers) at universities, research institutions and industry in the areas of oncology, herbal cancer therapy, biotechnology, drug discovery, pharmaceuticals, agriculture, and various disciplines of the biomedical sciences.


Book
Cell Reprogramming for Immunotherapy : Methods and Protocols
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ISBN: 1071602020 1071602039 Year: 2020 Publisher: New York, NY : Springer US : Imprint: Humana,

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This volume details key protocols for developing strategies in immunotherapy. Chapters guide the readers through protocols related to various DNA, RNA and protein methods to reprogram the immune system, immune cells, analyzing the effect of the reprogrammed cells, and key methods to consider and analyze patients enrolled in clinical trials with novel immunotherapy regimens. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cell Reprogramming for Immunotherapy: Methods and Protocols aims to ensure successful results in the further study of this vital field.


Book
Pericytes : Methods and Protocols
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ISBN: 1071610562 1071610554 Year: 2021 Publisher: New York, NY : Springer US : Imprint: Humana,

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This volume explores the techniques used to study human and animal pericytes. Chapters in this volume cover a range of topics such as pericyte dissociation from tissues, and analysis by immunohistochemistry and flow cytometry; avian chimaeras to investigate the embryonic development of cell lineage; pericyte purification by fluorescence activated cell sorting and ensuing culture; tissue turnover and regeneration; and the dynamic study of pericyte involvement in cancer dissemination, in situ, and in culture. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Pericytes: Methods and Protocols is a valuable resource that helps researchers define the biologic identity, functions, and potentials of a cell lineage of increasing interest and therapeutic significance. .

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