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Mesenchymal stem cells. --- Cancer --- Chemotherapy. --- Antineoplastic agents --- Bone marrow stromal cells --- Marrow stromal cells --- MSCs (Mesenchymal stem cells) --- Stromal cells, Bone marrow --- Stromal cells, Marrow --- Multipotent stem cells --- Treatment
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Multipotent mesenchymal stem cells (MSCs) are a heterogeneous population of cells which reside in a variety of tissues. They differentiate into several mesodermal lineages, secrete a multitude of trophic factors and contribute to tissue homeostasis. MSCs are able to exert immunosuppressive activities by interfering with inflammatory cytokine production and with T- and B-cell proliferation. These immunomodulating properties make MSCs promising candidates for the treatment of chronic inflammatory and autoimmune disorders. There are, however, certain caveats involved including inappropriate migration of cells in the body, immune rejection, tumor formation, or graft versus host disease (GvHD). This book investigates the current state of the MSC-dependent therapy of chronic inflammatory disorders and autoimmune diseases. Among the covered topics are GvHD, chronic kidney, liver and lung disease, ischemic heart and inflammatory bowel disease, diabetes, osteoarthritis, various rheumatic and neurological disorders and, lastly, tumors and solid organ transplantations. This book also questions the immunoprivileged status of MSCs, discusses the therapeutic role of MSCs in experimental animal disease models and their translation to the corresponding human disorders, envisions a role for MSCs in tumor interventions and, lastly, describes a systems biology approach for stem cells and inflammation.
Inflammation. --- Mesenchymal stem cells --- Bone marrow stromal cells --- Marrow stromal cells --- MSCs (Mesenchymal stem cells) --- Stromal cells, Bone marrow --- Stromal cells, Marrow --- Multipotent stem cells --- Inflammatory process --- Pathology --- Anti-inflammatory agents --- Transplantation. --- Autoimmune Disorders. --- Immunomodulation. --- Regenerative Medicine. --- Stem Cells.
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This monograph provides a current and in-depth review of scholarly information about mesenchymal stem cells and their application in the craniofacial region of the human body. Chapters in this volume cover biological and conceptual information about mesenchymal stem cells, induced pluripotent stem cells, craniofacial regeneration, new methods of scaffold fabrication, tooth regeneration and three-dimensional printing in dentistry. The book is suitable for clinicians and cell biologists aiming to gain a better understanding of the promising field of craniofacial regenerative medicine.
Mesenchymal stem cells. --- Regeneration (Biology) --- Regenerative biology --- Regrowth (Biology) --- Developmental biology --- Autotomy --- Wound healing --- Bone marrow stromal cells --- Marrow stromal cells --- MSCs (Mesenchymal stem cells) --- Stromal cells, Bone marrow --- Stromal cells, Marrow --- Multipotent stem cells
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This book explores dental stem cell (DSC) biology, from a review of basic concepts for cell culture, to isolation, self-renewal, multipotency and differentiation, regulation by molecular medicine, and prospective research areas for regenerative medicine. The first seven chapters delve into basic DSC properties, vital signaling pathways involved in differentiation, pluripotency, iPS cell development from DSCs, and genetic engineering approaches of DSCs in accordance with the current literature. A comprehensive review of possible clinical applications and in vitro/in vivo studies follows, illustrating the future of DSC research for in the tissue engineering field. The text also discusses the political, ethical, social, and legal ramifications of the use of dental stem cells. Expertly authored and drawing from a multitude of international perspectives, Dental Stem Cells is an invaluable addition to Springer's Stem Cell Biology and Regenerative Medicine series. It is essential reading for advanced graduate students, basic researchers, and clinical investigators in the fields of stem cell therapy, biological sciences of dentistry, and regenerative medicine.
Life sciences. --- Stem cells. --- Regenerative medicine. --- Tissue engineering. --- Life Sciences. --- Stem Cells. --- Regenerative Medicine/Tissue Engineering. --- Mesenchymal stem cells. --- Bone marrow stromal cells --- Marrow stromal cells --- MSCs (Mesenchymal stem cells) --- Stromal cells, Bone marrow --- Stromal cells, Marrow --- Multipotent stem cells --- Colony-forming units (Cells) --- Mother cells --- Progenitor cells --- Cells --- Biomedical engineering --- Regenerative medicine --- Tissue culture --- Medicine --- Regeneration (Biology)
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Mesenchymal stem cells. --- Mesenchymal Stromal Cells. --- Bone marrow stromal cells --- Marrow stromal cells --- MSCs (Mesenchymal stem cells) --- Stromal cells, Bone marrow --- Stromal cells, Marrow --- Multipotent stem cells --- Adipose Tissue-Derived Mesenchymal Stem Cells --- Adipose Tissue-Derived Mesenchymal Stromal Cells --- Adipose-Derived Mesenchymal Stem Cells --- Adipose-Derived Mesenchymal Stromal Cells --- Bone Marrow Mesenchymal Stem Cells --- Bone Marrow Stromal Cell --- Bone Marrow Stromal Cells --- Bone Marrow Stromal Cells, Multipotent --- Bone Marrow Stromal Stem Cells --- Mesenchymal Progenitor Cell --- Mesenchymal Progenitor Cells --- Mesenchymal Stem Cell --- Mesenchymal Stem Cells, Adipose-Derived --- Mesenchymal Stromal Cells, Multipotent --- Multipotent Bone Marrow Stromal Cells --- Multipotent Mesenchymal Stromal Cells --- Stem Cells, Mesenchymal --- Wharton Jelly Cells --- Wharton's Jelly Cells --- Adipose Tissue-Derived Mesenchymal Stem Cell --- Adipose-Derived Mesenchymal Stem Cell --- Bone Marrow Mesenchymal Stem Cell --- Mesenchymal Stromal Cell --- Mesenchymal Stromal Cells --- Multipotent Bone Marrow Stromal Cell --- Multipotent Mesenchymal Stromal Cell --- Adipose Derived Mesenchymal Stem Cell --- Adipose Derived Mesenchymal Stem Cells --- Adipose Derived Mesenchymal Stromal Cells --- Adipose Tissue Derived Mesenchymal Stem Cell --- Adipose Tissue Derived Mesenchymal Stem Cells --- Adipose Tissue Derived Mesenchymal Stromal Cells --- Mesenchymal Stem Cells, Adipose Derived --- Progenitor Cell, Mesenchymal --- Progenitor Cells, Mesenchymal --- Stem Cell, Mesenchymal --- Stromal Cell, Mesenchymal --- Stromal Cells, Mesenchymal --- Wharton's Jelly Cell --- Whartons Jelly Cells
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With the thorough understanding of stem cell biology and the advent of targeted therapeutics for cancer, stem cell-based therapeutic strategies are being increasingly explored for the treatment of various cancer types. The aim of this publication is to shed light on current stem cell based targeted therapies for cancer, by focusing on the application of mesenchymal stem cells (MSC) in various cancers with emphasis on a number of aspects that are critical to the success of future stem cell based therapies for cancer. Different sections of this publication will be devoted to developing stem c
Mesenchymal stem cells. --- Cancer --- Treatment. --- Neoplasms --- Mesenchymal Stem Cell Transplantation. --- Mesenchymal Stem Cells --- physiology. --- Transplantation, Mesenchymal Stem Cell --- Stem Cell Transplantation, Mesenchymal --- Cancer therapy --- Cancer treatment --- Bone marrow stromal cells --- Marrow stromal cells --- MSCs (Mesenchymal stem cells) --- Stromal cells, Bone marrow --- Stromal cells, Marrow --- Multipotent stem cells --- transplantation --- Therapy --- Stem cells.
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Mesenchymal stem cells. --- Mesenchymal Stem Cells --- Adipose Tissue-Derived Mesenchymal Stem Cells --- Adipose Tissue-Derived Mesenchymal Stromal Cells --- Adipose-Derived Mesenchymal Stem Cells --- Adipose-Derived Mesenchymal Stromal Cells --- Bone Marrow Mesenchymal Stem Cells --- Bone Marrow Stromal Cell --- Bone Marrow Stromal Cells --- Bone Marrow Stromal Cells, Multipotent --- Bone Marrow Stromal Stem Cells --- Mesenchymal Progenitor Cell --- Mesenchymal Progenitor Cells --- Mesenchymal Stem Cell --- Mesenchymal Stem Cells, Adipose-Derived --- Mesenchymal Stromal Cells, Multipotent --- Multipotent Bone Marrow Stromal Cells --- Multipotent Mesenchymal Stromal Cells --- Stem Cells, Mesenchymal --- Wharton Jelly Cells --- Wharton's Jelly Cells --- Mesenchymal Stromal Cells --- Adipose Derived Mesenchymal Stem Cells --- Adipose Derived Mesenchymal Stromal Cells --- Adipose Tissue Derived Mesenchymal Stem Cells --- Adipose Tissue Derived Mesenchymal Stromal Cells --- Mesenchymal Stem Cells, Adipose Derived --- Mesenchymal Stromal Cell --- Progenitor Cell, Mesenchymal --- Progenitor Cells, Mesenchymal --- Stem Cell, Mesenchymal --- Stromal Cell, Mesenchymal --- Stromal Cells, Mesenchymal --- Wharton's Jelly Cell --- Whartons Jelly Cells --- Bone marrow stromal cells --- Marrow stromal cells --- MSCs (Mesenchymal stem cells) --- Stromal cells, Bone marrow --- Stromal cells, Marrow --- Multipotent stem cells --- Adipose Tissue-Derived Mesenchymal Stem Cell --- Adipose-Derived Mesenchymal Stem Cell --- Bone Marrow Mesenchymal Stem Cell --- Multipotent Bone Marrow Stromal Cell --- Multipotent Mesenchymal Stromal Cell --- Adipose Derived Mesenchymal Stem Cell --- Adipose Tissue Derived Mesenchymal Stem Cell
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Mesenchymal stem cells. --- Veterinary medicine. --- Farriery --- Large animal medicine --- Large animal veterinary medicine --- Livestock medicine --- Veterinary science --- Medicine --- Animal health --- Animals --- Domestic animals --- Livestock --- Bone marrow stromal cells --- Marrow stromal cells --- MSCs (Mesenchymal stem cells) --- Stromal cells, Bone marrow --- Stromal cells, Marrow --- Multipotent stem cells --- Diseases --- Losses
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"Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas--cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and looks toward the clinical applications of this exciting phenomenon, which is emerging as an effective diagnostic technique. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the first compendium for clinical and biomedical researchers who are interested in integrating MSC-derived exosomes as a diagnostic and therapeutic tool."--
Exosomes --- Nanomedicine --- Cardiovascular Diseases --- Nanotechnology --- Diseases --- Transport Vesicles --- Biomedical Technology --- Technology --- Cytoplasmic Vesicles --- Natural Science Disciplines --- Miniaturization --- Technology, Industry, and Agriculture --- Organelles --- Disciplines and Occupations --- Cytoplasmic Structures --- Technology, Industry, Agriculture --- Cytoplasm --- Intracellular Space --- Cellular Structures --- Cells --- Anatomy --- Cytology --- Biology --- Health & Biological Sciences --- Mesenchymal stem cells. --- Mesenchymal stem cells --- Differentiation. --- Cell differentiation --- Bone marrow stromal cells --- Marrow stromal cells --- MSCs (Mesenchymal stem cells) --- Stromal cells, Bone marrow --- Stromal cells, Marrow --- Multipotent stem cells
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