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Clinical health psychology --- Medicine and psychology --- Clinical health psychology. --- Medicine and psychology. --- Behavioral Medicine. --- Psychology, Clinical. --- behavioural medicine --- behavioural sciences --- health --- illness --- psychology --- psychosocial health --- Psychology --- Human medicine

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Six decades after the serendipitous discovery of chlorpromazine as an antipsychotic and four decades after the launch of clozapine, the first atypical or second generation antipsychotic, psychopharmacology has arrived at an important crossroad. It is clear that pharmacological research and pharmaceutical development must now focus on complementary or even alternative mechanisms of action to address unmet medical  needs, i.e. poorly treated domains of schizophrenia, improved acceptance by patients, better adherence to medication, safety in psychoses in demented patients, and avoiding cardiac and metabolic adverse effects. The first completely novel mechanisms evolving from our insights into the pathophysiology of psychotic disorders, especially the role of glutamatergic mechanisms in schizophrenia, are now under development, and further principles are on the horizon. This situation, in many respects similar to that when the initial second-generation antipsychotics became available, can be rewarding for all.  Preclinical and clinical researchers now have the opportunity to confirm their hypotheses and the pharmaceutical industry may be able to develop really novel classes of therapeutics. When we were approached by the publishers of the Handbook of Experimental Pharmacology to prepare a new volume on antipsychotics, our intention was to capture both, the accumulated preclinical and clinical knowledge about current antipsychotics as well as prospects for new and potentially more specific antischizophrenia principles. These efforts should be based on the pathophysiology of the diseases and the affected neurotransmitter systems. Since preclinical research on antipsychotic compounds is only reliable when intimately linked through translational aspects to clinical results, we decided to include clinical science as well. It turned out that that this endeavor could not be covered by a single volume. We thank the editorial board and the publishers for supporting our decision to prepare two volumes: Current Antipsychotics and Novel Antischizophrenia Treatments. These topics cannot really be separated from one another and should be seen as a composite entity despite the somewhat arbitrary separation of contributions into two volumes. The continuing challenges of developing improved and safer antipsychotic medications remain of concern and are discussed in the first volume. The new opportunities for the field to develop and license adjunctive treatments for the negative symptoms and cognitive deficits that are treated inadequately by existing compounds have been incentivized recently and provide the focus for the second volume. We hope these collective contributions will facilitate the development of improved treatments for the full range of symptomatology seen in the group of schizophrenias and other major psychotic disorders. Gerhard Gross, Ludwigshafen, Germany Mark A. Geyer, La Jolla, CA This volume will try to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters will also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. Non-schizophrenia indications will be covered to some extent, but not exhaustively.

Biomedicine. --- Pharmacology/Toxicology. --- Neurosciences. --- Receptors. --- Neurobiology. --- Behavioural Sciences. --- Pharmacy. --- Medicine. --- Toxicology. --- Animal behavior. --- Cell receptors. --- Médecine --- Neurosciences --- Toxicologie --- Pharmacie --- Animaux --- Récepteurs cellulaires --- Neurobiologie --- Moeurs et comportement --- Antipsychotic drugs. --- Schizophrenia --- Chemotherapy. --- Pathophysiology.

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humanities --- social sciences --- behavioural sciences --- Humanities --- Social sciences --- Social Sciences --- Humanities. --- Social sciences. --- Periodicals. --- Behavioral sciences --- Human sciences --- Sciences, Social --- Social science --- Social studies --- Civilization --- Learning and scholarship --- Classical education --- Science, Social --- Social Science --- Humanities.. --- Social Sciences.

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Touch may well be one of the least understood or talked about subjects in the helping professions. A discussion on the importance and ethics of positive, caring, and appropriate touch in professions such as teaching, nursing and counselling is long overdue. Touch in the Helping Professions delivers just that, weaving together scholarly evidence, research and clinical practice from a wide range of perspectives encompassing philosophy, theology, psychology, and anthropology to challenge assumptions about the role of touch in the helping professions.  The contributors to the volume focus not only on the overarching roles of gender, age, culture and life experience, but go beyond to encompass canine-assisted therapy, touch deprivation, sacred objects, as well as key ethical considerations. The prevailing lack of dialogue, due to fear of contravening ethical boundaries, has stood in the way of an open and responsible discussion on the use of touch in therapy. Touch in the Helping Professions is a welcome and much needed contribution to the field-a window onto a fundamental need. This book is published in English. - Cet ouvrage offre un ensemble de données probantes et de résultats cliniques à l'appui du toucher dans le développement physique et émotionnel. Il est structuré selon trois axes : la théorie sur le toucher; la pratique du toucher dans un contexte de thérapie, et les questions éthiques. Il aborde la question du rôle du genre, de l'âge, de la culture et de l'expérience de vie, des sujets comme la zoothérapie, la privation sensorielle, des objets sacrés, et des considérations d'ordre éthique. Les approches variées - philosophie, théologie, psychologie, anthropologie - remettent en question les présuppositions, offrent un contexte historico-culturelprofessionnel, et font appel à des données primaires.  Les collaborateurs soutiennent que le toucher sain et non sexuel n'est pas suffisamment enseigné dans le cadre de la formation professionnelle. Cette absence de dialogue - engendrée par la crainte de dépasser des bornes éthiques, fait en sorte qu'une discussion ouverte et responsable sur l'utilisation du toucher dans un cadre thérapeutique ne peut avoir lieu, alors même qu'elle contribuerait aux balises théoriques de notre compréhension de cet enjeu fondamental. Ce livre est publié en anglais.

Touch --- Therapeutic use. --- Healing touch --- Imposition of hands --- Therapeutic touch --- Energy medicine --- Therapeutic use --- Psychological aspects. --- Religious aspects. --- Aristotle --- Attachment theory --- Behavioural sciences --- Cognition --- Cognitive science --- Culture --- David hume --- Human activities --- Idea --- Meditations on first philosophy --- Health Care. --- Helping Professions. --- Social Services.

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Adolescence --- Youth --- Adolescent psychology --- Jeunesse --- Adolescents --- Adolescence. --- Adolescent psychology. --- Youth. --- Adolescent. --- Psychologie --- Health Sciences --- Social Sciences --- General and Others --- Behavioral Science (Psychology) and Counselling --- Demographic Studies --- Sociology --- Adolescents, Female --- Adolescents, Male --- Teenagers --- Teens --- Adolescent, Female --- Adolescent, Male --- Female Adolescent --- Female Adolescents --- Male Adolescent --- Male Adolescents --- Teen --- Teenager --- Youths --- Young people --- Young persons --- Youngsters --- Teen-age --- Psychology --- Development --- adolescent development --- behavioural sciences --- educational psychology --- Minors --- Age groups --- Life cycle, Human --- Puberty --- Adolescent --- Sociology of the family. Sociology of sexuality --- Teaching --- adolescenten