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Drug Therapy --- Epidemiologic Methods --- Drugs --- Epidemiology --- Médicaments --- Epidémiologie --- adverse effects --- Side effects --- Research --- Methodology --- Effets secondaires --- Recherche --- Méthodologie --- Drug-Related Side Effects and Adverse Reactions. --- Epidemiologic Methods. --- -Epidemiology --- -Diseases --- Public health --- Medicaments --- Medications --- Medicine (Drugs) --- Medicines (Drugs) --- Pharmaceuticals --- Prescription drugs --- Bioactive compounds --- Medical supplies --- Pharmacopoeias --- Chemotherapy --- Materia medica --- Pharmacology --- Pharmacy --- Epidemiologic Method --- Epidemiological Methods --- Methods, Epidemiologic --- Epidemiological Method --- Method, Epidemiologic --- Method, Epidemiological --- Methods, Epidemiological --- -Methodology --- methods --- -Side effects --- Médicaments --- Epidémiologie --- Méthodologie --- Drug-Related Side Effects and Adverse Reactions --- Adverse Drug Event --- Adverse Drug Reaction --- Drug Side Effects --- Drug Toxicity --- Side Effects of Drugs --- Toxicity, Drug --- Adverse Drug Events --- Adverse Drug Reactions --- Drug Event, Adverse --- Drug Events, Adverse --- Drug Reaction, Adverse --- Drug Reactions, Adverse --- Drug Related Side Effects and Adverse Reactions --- Drug Side Effect --- Drug Toxicities --- Effects, Drug Side --- Reactions, Adverse Drug --- Side Effect, Drug --- Side Effects, Drug --- Toxicities, Drug --- Pharmaceutical Preparations --- Contraindications, Drug --- Drug Interactions --- Clinical Trials, Phase IV as Topic --- Diseases --- Adverse drug reactions --- Adverse reactions to drug therapy --- Drug-induced disease --- Drug side effects --- Side effects of drugs --- Iatrogenic diseases --- Drug interactions --- Research&delete& --- toxicity --- Complications --- Adverse reactions --- Physiological effect --- DRUG THERAPY --- EPIDEMIOLOGIC METHODS --- ADVERSE EFFECTS

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Pharmacoepidemiology --- Pharmacology, Clinical. --- Pharmacoepidemiology --- Pharmacoépidémiologie --- methods.

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"It was a remarkable 32 years ago that the first edition of Strom's Pharmacoepidemiology was published. The preface to that book stated that pharmacoepidemiology was a new field with a new generation of pharmacoepidemiologists arising to join the field's few pioneers. Over the ensuing 32 years, the field indeed has grown and no longer deserves to be called "new." Many of those "new generation" scientists (including two of the editors of this book) are now "middle-aged" pharmacoepidemiologists. Despite its relatively brief academic life, a short history of pharmacoepidemiology and review of its current state will set the stage for the purpose of this textbook. Pharmacoepidemiology originally arose from the union of the fields of clinical pharmacology and epidemiology. Pharmacoepidemiology studies the use of and the effects of medical products in large numbers of people and applies the methods of epidemiology to the content area of clinical pharmacology. This field represents the science underlying postmarketing medical product surveillance, studies of the effects of medical products (i.e., drugs, biologicals, devices) performed after a product has been approved for use. In recent years, pharmacoepidemiology has expanded to include many other types of studies, as well"--

Pharmacoepidemiology --- Pharmacoépidémiologie --- methods --- Méthodes --- methods.

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"Hepatitis B and C cause most cases of hepatitis in the United States and the world. The two diseases account for about a million deaths a year and 78 percent of world's hepatocellular carcinoma and more than half of all fatal cirrhosis. In 2013 viral hepatitis, of which hepatitis B virus (HBV) and hepatitis C virus (HCV) are the most common types, surpassed HIV and AIDS to become the seventh leading cause of death worldwide. The world now has the tools to prevent hepatitis B and cure hepatitis C. Perfect vaccination could eradicate HBV, but it would take two generations at least. In the meantime, there is no cure for the millions of people already infected. Conversely, there is no vaccine for HCV, but new direct-acting antivirals can cure 95 percent of chronic infections, though these drugs are unlikely to reach all chronically-infected people anytime soon. This report, the first of two, examines the feasibility of hepatitis B and C elimination in the United States and identifies critical success factors. The phase two report will outline a strategy for meeting the elimination goals discussed in this report"--

Hepatitis B --- Hepatitis C --- Prevention. --- United States.

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