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This succinct volume addresses the production of inactive, potentially toxic proteins in the absence of correct protein folding and the resultant neurodegenerative diseases. Other topics include intrinsic disorder in protein structure and function and the effects of molten globules on protein toxicity. This concise and yet thorough text also discusses using toxin structure as a model for studying structural and functional aspects of protein chemistry. Protein Toxins in Modeling Biochemistry, a SpringerBrief, is essential reading for advanced researchers, scientists and advanced graduate students interested in protein chemistry and related areas of biochemistry and molecular science. .

Life sciences. --- Microbiology. --- Proteomics. --- Proteins. --- Life Sciences. --- Protein Science. --- Protein Structure. --- Protein-Ligand Interactions. --- Applied Microbiology. --- Cytology. --- Biochemistry. --- Microbial biology --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Cell biology --- Cellular biology --- Composition --- Biology --- Microorganisms --- Chemistry --- Medical sciences --- Cells --- Cytologists --- RNA-ligand interactions. --- Molecular biology --- Proteins --- Proteins . --- Proteids --- Biomolecules --- Polypeptides --- Proteomics

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This succinct volume addresses the production of inactive, potentially toxic proteins in the absence of correct protein folding and the resultant neurodegenerative diseases. Other topics include intrinsic disorder in protein structure and function and the effects of molten globules on protein toxicity. This concise and yet thorough text also discusses using toxin structure as a model for studying structural and functional aspects of protein chemistry. Protein Toxins in Modeling Biochemistry, a SpringerBrief, is essential reading for advanced researchers, scientists and advanced graduate students interested in protein chemistry and related areas of biochemistry and molecular science. .

Chemical structure --- Chemistry --- Genetics --- General microbiology --- Biology --- Pharmacology. Therapy --- Medical microbiology, virology, parasitology --- toegepaste microbiologie --- moleculaire structuur --- protein-ligand binding constant --- protein-engineering --- proteomics --- farmacologie --- biologie --- microbiologie --- eiwitten --- moleculaire biologie --- proteïnen

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Toxins --- Congresses

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Biological toxins are an important part of our world, a reality with which we need to cope, so in parallel with understanding their mechanisms of action and thereby improving our fundamental knowledge, there are successful efforts to utilize them as therapeutics against some debilitating human and animal diseases. In view of the complexity of different types of biotoxins and the broad range of toxin structure, physiology, utility, and countermeasures including regulatory issues, it was thus aimed to compile a book on biotoxins and bioweapons.   This reference work in the Toxinology handbook series gathers together knowledge from around the globe about naturally inspired and manufactured biological weapons. The authors describe how they work; how authorities may detect their presence, prevent their use, and diagnose their impacts; and the means by which medical and paramedical professionals may treat victims. Also described are how they have been used to further our knowledge and what insights they have given us into evolutionary and physiological processes. Finally, it is also discussed how these toxins can be used as therapeutics and what the implications of such therapeutics are to their use as biothreat agents.   This volume provides a reference accessible to scientists, educators, and medical experts alike with an interest in biotoxins, focusing on the major toxins used as bioweapons. Regulatory agencies will also benefit from the information provided in this book. Some in the intended audience may need to understand how they elicit their effects and how we can defend ourselves against them. Others may be interested in the sometimes colorful histories that surround this subset of biotoxins that can be and, in some cases, have been used as weapons.

Biomedicine. --- Pharmacology/Toxicology. --- Pharmaceutical Sciences/Technology. --- Life Sciences, general. --- Animal Biochemistry. --- Animal Physiology. --- Medicine. --- Toxicology. --- Pharmaceutical technology. --- Life sciences. --- Biochemistry. --- Médecine --- Toxicologie --- Techniques pharmaceutiques --- Sciences de la vie --- Biochimie --- Health & Biological Sciences --- Pharmacy, Therapeutics, & Pharmacology --- Animal physiology --- Animals --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biosciences --- Sciences, Life --- Pharmaceutical laboratory techniques --- Pharmaceutical laboratory technology --- Technology, Pharmaceutical --- Chemicals --- Clinical sciences --- Medical profession --- Physiology --- Composition --- Toxicology --- Pharmacology. --- Animal physiology. --- Biology --- Chemistry --- Medical sciences --- Science --- Technology --- Human biology --- Life sciences --- Pathology --- Physicians --- Anatomy --- Drug effects --- Medical pharmacology --- Chemotherapy --- Drugs --- Pharmacy --- Physiological effect --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Biological weapons. --- Bacteriological weapons --- Biological warfare agents --- Bioweapons --- Weapons of mass destruction --- Biosecurity --- Biological monitoring. --- Biological warfare. --- Bioterrorism. --- Biologic monitoring --- Biomonitoring (Toxicology) --- Monitoring, Biological --- Indicators (Biology) --- Bio-terrorism --- Biological terrorism --- Bioterrorism --- Terrorism --- Bacterial warfare --- Bacteriological warfare --- Biowarfare --- CBR warfare --- Disease warfare --- Germ warfare --- Pathogenic bacteria --- Bioengineering --- War --- Analysis --- Law and legislation --- War use --- Cold War Biological warfare --- Biological warfare