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This volume gives a state-of-the-art overview on macrophage functions in various invertebrate and vertebrate systems and diseases. It also covers various aspects of macrophage development and formation, behavior and response to nano- and biomaterials, the latter of which have become very important components of modern medicine. Macrophages are evolutionarily conserved phagocytotic cells. In recent years macrophages have emerged as one of the most versatile cells of immune system, which, depending on the milieu and circumstance, participate in development or inhibition of cancer, regeneration, wound healing, inflammation, organ rejection and interaction between mother and a fetus. This book will be of particular interest to researchers working in immunology, cancer research, developmental biology, or related fields.
Medicine. --- Cancer research. --- Immunology. --- Medical microbiology. --- Developmental biology. --- Biomaterials. --- Biomedicine. --- Developmental Biology. --- Cancer Research. --- Medical Microbiology. --- Macrophages. --- Histiocytes --- Mononuclear phagocytes --- Antigen presenting cells --- Connective tissue cells --- Killer cells --- Phagocytes --- Reticulo-endothelial system --- Oncology. --- Microbiology. --- Biocompatible materials --- Biomaterials --- Medical materials --- Medicine --- Biomedical engineering --- Materials --- Biocompatibility --- Prosthesis --- Microbial biology --- Biology --- Microorganisms --- Tumors --- Development (Biology) --- Growth --- Ontogeny --- Immunobiology --- Life sciences --- Serology --- Bioartificial materials --- Hemocompatible materials --- Cancer research --- Biomaterials (Biomedical materials)
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This book combines the most recent knowledge on the maternal, i.e. oocyte/egg-specific, molecules and processes. The volume covers the most recent advances in a plethora of subjects such as: maternal transfer of immunity, localized RNAs functions and mechanisms of RNA localization, transcriptional repression of maternal messages, maternal inheritance and maternal role of CRISPR/Cas9-based genome editing, chromatin remodeling and epigenetic modifications, maternal function of nucleosomes, maternal mitochondria and energy supply, role of bacterial symbionts and their maternal transmission, acquisition of oocyte polarity and evolution of maternal effect genes, germ plasm and oosome origin and functions, mechanisms of oocyte activation and soma germ cells communication. Currently, no other book on the market combines such a comprehensive list of subjects in one volume. Moreover, the information provided is a cross-section through oocytes from various invertebrate a nd vertebrate species, which is another unique feature of this book. The readers, therefore, get a completely new and invaluable perspective on all covered subjects. .
Ovum. --- Egg (Cytology) --- Egg cell --- Female gamete --- Oocyte --- Ovocyte --- Secondary oocyte --- Life sciences. --- Gene expression. --- Reproductive medicine. --- Cell cycle. --- Cell physiology. --- Embryology. --- Life Sciences. --- Gene Expression. --- Cell Cycle Analysis. --- Cell Physiology. --- Reproductive Medicine. --- Gametes --- Human reproduction --- Human reproductive health --- Human reproductive medicine --- Reproductive medicine --- Health --- Cell function --- Cytology --- Physiology --- Mitotic cycle --- Nuclear cycle (Cytology) --- Biological rhythms --- Genes --- Genetic regulation --- Animal embryology --- Animals --- Development, Embryological --- Development, Embryonic --- Development, Zygotic --- Embryogenesis --- Embryogeny --- Embryological development --- Embryonic development --- Zoology --- Zygote development --- Zygotes --- Zygotic development --- Zygotic embryogenesis --- Developmental biology --- Morphology (Animals) --- Embryos --- Reproduction --- Health aspects --- Expression --- Embryology --- Development --- Molecular genetics. --- Cytology. --- Reproductive health. --- Molecular Genetics. --- Cytological Techniques. --- Cell Biology. --- Technique. --- Cell biology --- Cellular biology --- Biology --- Cells --- Genetics --- Molecular biology
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This volume takes a closer look how the cell organelles Golgi apparatus (also known as the Golgi complex or Golgi body), and centriole are structurally and functionally intertwined. Initially, it was believed that the role of Golgi complex is limited to the packaging and preparation for secretion of various cellular proteins, while the centriole participates in cell division and cilia formation. However, since their discovery nearly 200 years ago, it became clear that these two organelles are interacting, and that their functions are much more complex and far reaching than previously thought. Recent findings indicate that the Golgi–Centriole relationship may be important for directional protein transport, cell polarization and cell cycle progression. Current studies indicate that Golgi and centriole also participate in development and act as cellular and immunological sensors, and that their abnormalities lead to cell and developmental abnormalities, Alzheimer, cancer, various lipid disorders and neurological and immunological diseases in humans. This volume combines the latest information on the structure, molecular composition, and roles of Golgi and centriole in various cellular functions and diseases. The better understanding of the Golgi–centriole interactions may lead to the development of novel therapies for the treatment of various diseases, including cancer. .
Golgi apparatus. --- Centrioles. --- Developmental biology. --- Cell cycle. --- Cell membranes. --- Oncology. --- Cell physiology. --- Biochemistry. --- Developmental Biology. --- Cell Cycle Analysis. --- Membrane Biology. --- Cancer Research. --- Cell Physiology. --- Protein Science. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Cell function --- Cytology --- Physiology --- Tumors --- Cell surfaces --- Cytoplasmic membranes --- Plasma membranes --- Plasmalemma --- Membranes (Biology) --- Glycocalyces --- Mitotic cycle --- Nuclear cycle (Cytology) --- Biological rhythms --- Development (Biology) --- Growth --- Ontogeny --- Composition --- Cell membranes . --- Cancer research. --- Proteins . --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- Cancer research --- Biological transport. --- Cancer. --- Cytology. --- Proteins. --- Developmental Biology and Stem Cells. --- Cytological Techniques. --- Membrane Trafficking. --- Cancer Biology. --- Cell Biology. --- Protein Biochemistry. --- Technique. --- Cell biology --- Cellular biology --- Cells --- Cancers --- Carcinoma --- Malignancy (Cancer) --- Malignant tumors --- Membrane transport --- Passive transport, Biological --- Physiological transport --- Transport, Biological --- Diffusion --- Osmosis
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This volume presents a comprehensive overview of the latest developments in symbiosis research. It covers molecular, organellar, cellular, immunologic, genetic and evolutionary aspects of symbiotic interactions in humans and other model systems. The book also highlights new approaches to interdisciplinary research and therapeutic applications. Symbiosis refers to any mutually beneficial interaction between different organisms. The symbiotic origin of cellular organelles and the exchange of genetic material between hosts and their bacterial and viral symbionts have helped shaped the current diversity of life. Recently, symbiosis has gained a new level of recognition, due to the realization that all organisms function as a holobiome and that any kind of interference with the hosts influences their symbionts and vice versa, and can have profound consequences for the survival of both. For example, in humans, the microbiome, i.e., the entirety of all the microorganisms living in association with the intestines, oral cavity, urogenital system and skin, is partially inherited during pregnancy and influences the maturation and functioning of the human immune system, protects against pathogens and regulates metabolism. Symbionts also regulate cancer development, wound healing, tissue regeneration and stem cell function. The medical applications of this new realization are vast and largely uncharted. The composition and robustness of human symbionts could make them a valuable diagnostic tool for predicting impending diseases, and the manipulation of symbionts could yield new strategies for the treatment of incurable diseases.
Evolutionary biology. --- Microbiology. --- Virology. --- Genetics. --- Evolutionary Biology. --- Genetics and Genomics. --- Biology --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology) --- Microbiology --- Microbial biology --- Microorganisms --- Animal evolution --- Animals --- Biological evolution --- Darwinism --- Evolutionary biology --- Evolutionary science --- Origin of species --- Evolution --- Biological fitness --- Homoplasy --- Natural selection --- Phylogeny
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This volume gives a state-of-the-art overview on macrophage functions in various invertebrate and vertebrate systems and diseases. It also covers various aspects of macrophage development and formation, behavior and response to nano- and biomaterials, the latter of which have become very important components of modern medicine. Macrophages are evolutionarily conserved phagocytotic cells. In recent years macrophages have emerged as one of the most versatile cells of immune system, which, depending on the milieu and circumstance, participate in development or inhibition of cancer, regeneration, wound healing, inflammation, organ rejection and interaction between mother and a fetus. This book will be of particular interest to researchers working in immunology, cancer research, developmental biology, or related fields.
General embryology. Developmental biology --- General microbiology --- General biophysics --- Immunology. Immunopathology --- Oncology. Neoplasms --- Medical microbiology, virology, parasitology --- immunologie --- medische microbiologie --- biologische materialen --- microbiologie --- foetus --- oncologie --- embryologie (geneeskunde)
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This book combines the most recent knowledge on the maternal, i.e. oocyte/egg-specific, molecules and processes. The volume covers the most recent advances in a plethora of subjects such as: maternal transfer of immunity, localized RNAs functions and mechanisms of RNA localization, transcriptional repression of maternal messages, maternal inheritance and maternal role of CRISPR/Cas9-based genome editing, chromatin remodeling and epigenetic modifications, maternal function of nucleosomes, maternal mitochondria and energy supply, role of bacterial symbionts and their maternal transmission, acquisition of oocyte polarity and evolution of maternal effect genes, germ plasm and oosome origin and functions, mechanisms of oocyte activation and soma germ cells communication. Currently, no other book on the market combines such a comprehensive list of subjects in one volume. Moreover, the information provided is a cross-section through oocytes from various invertebrate a nd vertebrate species, which is another unique feature of this book. The readers, therefore, get a completely new and invaluable perspective on all covered subjects. .
General embryology. Developmental biology --- Genetics --- Histology. Cytology --- Molecular biology --- Gynaecology. Obstetrics --- embryologie (biologie) --- CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/Cas9) --- gynaecologie --- cytologie --- embryologie (geneeskunde) --- vroedkunde --- celprocessen --- moleculaire biologie --- genexpressie
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This volume presents a comprehensive overview of the latest developments in symbiosis research. It covers molecular, organellar, cellular, immunologic, genetic and evolutionary aspects of symbiotic interactions in humans and other model systems. The book also highlights new approaches to interdisciplinary research and therapeutic applications. Symbiosis refers to any mutually beneficial interaction between different organisms. The symbiotic origin of cellular organelles and the exchange of genetic material between hosts and their bacterial and viral symbionts have helped shaped the current diversity of life. Recently, symbiosis has gained a new level of recognition, due to the realization that all organisms function as a holobiome and that any kind of interference with the hosts influences their symbionts and vice versa, and can have profound consequences for the survival of both. For example, in humans, the microbiome, i.e., the entirety of all the microorganisms living in association with the intestines, oral cavity, urogenital system and skin, is partially inherited during pregnancy and influences the maturation and functioning of the human immune system, protects against pathogens and regulates metabolism. Symbionts also regulate cancer development, wound healing, tissue regeneration and stem cell function. The medical applications of this new realization are vast and largely uncharted. The composition and robustness of human symbionts could make them a valuable diagnostic tool for predicting impending diseases, and the manipulation of symbionts could yield new strategies for the treatment of incurable diseases.
Evolution. Phylogeny --- Genetics --- General microbiology --- Medical microbiology, virology, parasitology --- microbiologie --- genetica --- virologie --- Europees recht
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This book gives a current overview on the development, origin, structure, and functions of germline and somatic cell syncytia during embryogenesis and organogenesis. It also reviews pathogen-induced syncytia and the role of syncytial cells in cancer development. The book covers the following topics: germline syncytia, evolution, function and structure; syncytia in embryogenesis and development; the role of somatic cell fusion in fungi, specialized somatic tissues, host defense and adaptation; syncytia induced by viruses and parasites; syncytia and circulating hybrid cells in cancer and other pathological conditions; It also discusses how the genomic adaptations of microorganisms to extreme habitats can prompt the evolution of mononuclear and multinucleate/syncytial cells. The book offers a fresh outlook on syncytia's role in various processes: embryogenesis, organogenesis, adaptation, host defense, and development of specialized tissues. It highlights the importance of syncytia under physiological and pathological conditions.
Cell differentiation. --- Developmental biology. --- Stem cells. --- Cytology. --- Cell Differentiation. --- Developmental Biology and Stem Cells. --- Stem Cell Biology. --- Cell Biology.
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General embryology. Developmental biology --- Histology. Cytology --- cytologie --- embryologie (geneeskunde) --- stamceltransplantatie --- histologie
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This book highlights the potential advantages of using marine invertebrates like tunicates, echinoderms, sponges and cephalopods as models in both biological and medical research. Bioactive compounds found in marine organisms possess antibacterial, antifungal, anti-diabetic and anti-inflammatory properties, and can affect the immune and nervous systems. Despite substantial research on the medicinal attributes of various marine invertebrates, they are still very much underrepresented in scientific literature: the majority of cell, developmental and evolutionary scientific journals only publish research conducted on a few well-known model systems like Drosophila melanogaster or Xenopus laevis. Addressing that gap, this book introduces readers to new model organisms like starfish or nemertera. By showing their benefits with regard to regeneration, stem cell research and Evo-Devo, the authors provide a cross-sectional view encompassing various disciplines of biological research. As such, this book will not only appeal to scientists currently working on marine organisms, but will also inspire future generations to pursue research of their own.
Marine organisms. --- Marine biology. --- Biological oceanography --- Ocean biology --- Oceanic biology --- Sea biology --- Aquatic biology --- Marine sciences --- Aquatic organisms --- Marine biology --- Laboratory animals. --- Invertebrates. --- Developmental biology. --- Cytology. --- Immunology. --- Animal Models. --- Developmental Biology. --- Cell Biology. --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- Immunobiology --- Life sciences --- Serology --- Development (Biology) --- Growth --- Ontogeny --- Invertebrata --- Animals --- Animals, Experimental --- Animals, Laboratory --- Animals in research --- Experimental animals --- Lab animals --- Animal culture --- Laboratory organisms --- Working animals --- Animal experimentation --- Animal models in research. --- Cell biology. --- Biological models --- Laboratory animals --- Research --- Experimental Organisms. --- Developmental Biology and Stem Cells. --- Technique.
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