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Completely revised and updated, the 2nd edition of The "Handbook of Medicinal Chemistr"y draws together contributions from authoritative practitioners to provide a comprehensive overview of the field as well as insight into the latest trends and research. An ideal companion for students in medicinal chemistry, drug discovery and drug development, while also communicating core principles, the book places the discipline within the context of the burgeoning platform of new modalities now available to drug discovery. The book also highlights the role chemistry has to play in wider target validation and translational technologies.This is a carefully curated compilation of writing from global experts using their broad experience of medicinal chemistry, project leadership and drug discovery and development from an industry, academic and charity perspective to provide unparalleled insight into the field.

Clinical chemistry. --- Clinical biochemistry. --- Clinical pharmacology. --- Pharmaceutical chemistry. --- Drug development. --- Chimie clinique. --- Biochimie clinique. --- Pharmacologie clinique. --- Chimie pharmaceutique. --- Développement de médicament. --- Pharmacosynthesis. Pharmacochemistry --- Développement de médicament.

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This book newly articulates the international and interdisciplinary reach of Whitehead’s organic process cosmology for a variety of topics across science and philosophy, and in dialogue with a variety historical and contemporary voices. Integrating Whitehead’s thought with the insights of Bergson, James, Pierce, Merleau-Ponty, Descola, Fuchs, Hofmann, Grof and many others, contributors from around the world reveal the relevance of process philosophy to physics, cosmology, astrobiology, ecology, metaphysics, aesthetics, psychedelics, and religion. A global collection, this book expresses multivocal possibilities for the development of process cosmology after Whitehead. This book newly articulates the international and interdisciplinary reach of Whitehead’s organic process cosmology for a variety of topics across science and philosophy, and in dialogue with a variety historical and contemporary voices. Integrating Whitehead’s thought with the insights of Bergson, James, Pierce, Merleau-Ponty, Descola, Fuchs, Hofmann, Grof and many others, contributors from around the world reveal the relevance of process philosophy to physics, cosmology, astrobiology, ecology, metaphysics, aesthetics, psychedelics, and religion. A global collection, this book expresses multivocal possibilities for the development of process cosmology after Whitehead.

Cosmology. --- Astronomy --- Deism --- Metaphysics --- Metaphysics. --- Science --- Religion --- Ontology. --- Philosophy of Science. --- Philosophy of Religion. --- Philosophy. --- Being --- Philosophy --- Necessity (Philosophy) --- Substance (Philosophy) --- Normal science --- Philosophy of science --- God --- Ontology --- Philosophy of mind

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Completely revised and updated, the 2nd edition of The Handbook of Medicinal Chemistry draws together contributions from authoritative practitioners to provide a comprehensive overview of the field as well as insight into the latest trends and research. An ideal companion for students in medicinal chemistry, drug discovery and drug development, while also communicating core principles, the book places the discipline within the context of the burgeoning platform of new modalities now available to drug discovery. The book also highlights the role chemistry has to play in wider target validation and translational technologies. This is a carefully curated compilation of writing from global experts using their broad experience of medicinal chemistry, project leadership and drug discovery and development from an industry, academic and charity perspective to provide unparalleled insight into the field.

Pharmaceutical chemistry --- Drug development

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"Comprehensive Medicinal Chemistry III provides a contemporary and forward-looking critical analysis and summary of recent developments, emerging trends, and recently identified new areas where medicinal chemistry is having an impact. The discipline of medicinal chemistry continues to evolve as it adapts to new opportunities and strives to solve new challenges. These include drug targeting, biomolecular therapeutics, development of chemical biology tools, data collection and analysis, in silico models as predictors for biological properties, identification and validation of new targets, approaches to quantify target engagement, new methods for synthesis of drug candidates such as green chemistry, development of novel scaffolds for drug discovery, and the role of regulatory agencies in drug discovery. Reviews the strategies, technologies, principles, and applications of modern medicinal chemistry -- Provides a global and current perspective of today's drug discovery process and discusses the major therapeutic classes and targets -- Includes a unique collection of case studies and personal assays reviewing the discovery and development of key drugs" -- Provided by the publisher

Chemistry, Pharmaceutical