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Liposomes. --- Liposomes, Ultra-deformable --- Niosomes --- Transferosomes --- Ultradeformable Liposomes --- Liposome --- Liposome, Ultra-deformable --- Liposome, Ultradeformable --- Liposomes, Ultra deformable --- Liposomes, Ultradeformable --- Niosome --- Transferosome --- Ultra-deformable Liposome --- Ultra-deformable Liposomes --- Ultradeformable Liposome --- Lipid Bilayers --- Liposomes --- Liposomen --- Phospholipid vesicles --- Bilayer lipid membranes --- Cytoplasm --- Phospholipids --- Handbooks, manuals, etc --- Handbooks, manuals, etc. --- Liposomes - Handbooks, manuals, etc

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Nanovesicles are highly-promising systems for the delivery and/or targeting of drugs, biomolecules and contrast agents. Despite the fact that initial studies in this area were performed on phospholipid vesicles, there is an ever-increasing interest in the use of other molecules to obtain smart vesicular carriers focusing on strategies for targeted delivery. These systems can be obtained using newly synthesized smart molecules, or by intelligent design of opportune carriers to achieve specific delivery to the site of action.

n/a --- protein corona --- buspirone --- drug delivery --- Plectranthus ecklonii --- antiproliferative activity --- pancreatic ductal adenocarcinoma --- tetraethyl orthosilicate --- cancer therapy --- nanoparticles --- cationic liposomes --- Ibuprofen --- SBA-15 --- gastrointestinal stability --- mesoporous silica nanoparticles --- Parvifloron D --- anti-tumor drugs --- liposomes --- gingiva mesenchymal stromal cells --- soy lecithin liposomes --- MCM-41 --- lipophilic compound --- multifunctional liposomes --- caryophyllene sesquiterpene --- drug loading --- lamellarity --- hCMEC/D3 cells --- gold shell --- magnetic/plasmonic nanoparticles --- pH-sensitive niosomes --- hot flushes --- nasal delivery system --- andrographolide --- brain delivery --- pancreatic cancer --- Pain --- exosomes --- NSAIDs --- freeze-drying --- manganese ferrite --- surfactant --- cytotoxicity --- paclitaxel --- ovariectomized rat --- PAMPA --- uptake and safety --- nanovesicular nasal carrier --- Stober’s synthesis --- Analgesia --- protocells --- nanocochleates --- squamous cell carcinoma --- Stober's synthesis

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The Special Issue “Nanostructured Materials Based on Noble Metals for Advanced Biological Applications” highlights the recent progress in gold and silver nanomaterials preparation/synthesis as well as their innovative applications in advanced applications, such as in nanomedicine and nanosensors. It is nowadays generally accepted that nanostructured noble metals allow the production of highly competitive materials. In fact, a specific design and rather simple and reliable preparation techniques can be used to obtain optimized material uses and possibilities for their reusability. One expects amazing future developments for these nanotechnologies from research laboratories to key industrial areas. The Guest Editor and the MDPI staff are therefore pleased to offer this Special Issue to interested readers, including researchers, graduate and PhD students as well as postdoctoral researchers, but also to the entire community interested in the wide world of nanomaterials.

Technology: general issues --- gold --- nanostructure --- EDTA tetrasodium salt --- photothermal therapy --- silver nanoparticles --- biomedical applications --- biological interactions --- biofunctional performances --- intrinsic anti-inflammatory activity --- antimicrobial efficiency --- localized surface plasmon resonance --- dip-coating --- capillary force --- exosome --- gold nanoparticles --- copper(I) complexes --- conjugates --- drug delivery --- anticancer compounds --- niosomes --- liposomes --- plasmonic materials --- nanocarriers --- Hg2+ sensors --- heavy metal sensing --- plasmonic sensors --- optical sensors --- ecosafety --- nanoparticles --- interactions --- protein corona --- nanomedicine --- biomolecules --- nanomaterials --- noble metal nanoparticles --- gold nanomaterials --- silver nanomaterials --- hybrid metal–polymer nanoparticles --- biotechnological applications --- nanomaterials for drug delivery --- nanomaterials for sensing --- gold --- nanostructure --- EDTA tetrasodium salt --- photothermal therapy --- silver nanoparticles --- biomedical applications --- biological interactions --- biofunctional performances --- intrinsic anti-inflammatory activity --- antimicrobial efficiency --- localized surface plasmon resonance --- dip-coating --- capillary force --- exosome --- gold nanoparticles --- copper(I) complexes --- conjugates --- drug delivery --- anticancer compounds --- niosomes --- liposomes --- plasmonic materials --- nanocarriers --- Hg2+ sensors --- heavy metal sensing --- plasmonic sensors --- optical sensors --- ecosafety --- nanoparticles --- interactions --- protein corona --- nanomedicine --- biomolecules --- nanomaterials --- noble metal nanoparticles --- gold nanomaterials --- silver nanomaterials --- hybrid metal–polymer nanoparticles --- biotechnological applications --- nanomaterials for drug delivery --- nanomaterials for sensing

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Drug carriers (Pharmacy) --- Excipients --- Pharmaceutical Preparations. --- Liposomes. --- Macromolecular Substances. --- Pharmaceutical Vehicles. --- -Drug targeting --- -Drugs --- -Liposomes --- -Phospholipid vesicles --- Bilayer lipid membranes --- Cytoplasm --- Phospholipids --- Medicaments --- Medications --- Medicine (Drugs) --- Medicines (Drugs) --- Pharmaceuticals --- Prescription drugs --- Bioactive compounds --- Medical supplies --- Pharmacopoeias --- Chemotherapy --- Materia medica --- Pharmacology --- Pharmacy --- Drugs --- Site-specific drug delivery --- Targeting of drugs --- Target organs (Anatomy) --- Carriers, Drug (Pharmacy) --- Drug carrier systems (Pharmacy) --- Drug vehicles (Pharmacy) --- Vehicles, Drug (Pharmacy) --- Drug delivery systems --- Pharmaceutical Vehicle --- Vehicle, Pharmaceutical --- Vehicles, Pharmaceutical --- Macromolecular Complexes --- Macromolecular Compounds --- Macromolecular Compounds and Complexes --- Complexes, Macromolecular --- Compounds, Macromolecular --- Substances, Macromolecular --- Nanostructures --- Liposomes, Ultra-deformable --- Niosomes --- Transferosomes --- Ultradeformable Liposomes --- Liposome --- Liposome, Ultra-deformable --- Liposome, Ultradeformable --- Liposomes, Ultra deformable --- Liposomes, Ultradeformable --- Niosome --- Transferosome --- Ultra-deformable Liposome --- Ultra-deformable Liposomes --- Ultradeformable Liposome --- Lipid Bilayers --- Pharmaceutic Preparations --- Pharmaceutical Products --- Preparations, Pharmaceutical --- Preparations, Pharmaceutic --- Products, Pharmaceutical --- Drug Dosage Calculations --- Congresses --- Effectivness --- -Congresses --- Targeting --- Dosage forms --- Carriers --- Vehicles --- Drug targeting --- Liposomes --- Macromolecular Substances --- Pharmaceutical Preparations --- Pharmaceutical Vehicles --- Phospholipid vesicles --- Effectiveness&delete& --- Drug --- Pharmaceutical --- Pharmaceutical Preparation --- Pharmaceutical Product --- Preparation, Pharmaceutical --- Product, Pharmaceutical --- Effectiveness --- Cells. --- Cells --- Particles --- Pharmaceutical preparations --- Polymers

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Lipid-based nanosystems, including solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs), cationic lipid nanoparticles, nanoemulsions, and liposomes, have been extensively studied to improve drug delivery through different administration routes. The main advantages of these systems are their ability to protect, transport, and control the release of lipophilic and hydrophilic molecules (either small-molecular-weight molecules or macromolecules); the use of generally recognized as safe (GRAS) excipients that minimize the toxicity of the formulations; and the possibility to modulate pharmacokinetics and enable the site-specific delivery of encapsulated payloads. In addition, the versatility of lipid-based nanosystems has further been demonstrated for the delivery of vaccines, the protection of active cosmetic ingredients, and the improvement of moisturizing properties of cosmetic formulations.Lipid-based nanosystems are well established and there are already different commercially approved formulations for various human disorders. This success has paved the way for the diversification of the pipeline of development, to address unmet medical needs for several indications, such as cancer, neurological disorders, and autoimmune, genetic, and infectious diseases.This Special Issue aims to update readers on the latest research on lipid-based nanosystems, both at the preclinical and clinical levels. A series of 15 articles (six reviews and nine studies) is presented, with authors from 12 different countries, showing the globality of the investigations that are being carried out in this area.

Technology: general issues --- Echinococcus granulosus --- scolicidal --- nanoliposome --- juglone --- apoptotic activity --- hydrogel --- SLNs --- nose-to-brain delivery --- mucoadhesion --- quality by design --- antioxidant activity --- nasal administration --- nanostructured lipid carriers --- solid lipid nanoparticles --- in vitro cell cultures --- 3D nasal casts --- lung cancer --- targeted drug delivery --- lipid-based nanocarriers --- pulmonary delivery --- dry powder inhalers --- aerosols --- liposomes --- nanoemulsions --- nanotechnology --- biologically active compounds --- dermal drug delivery --- polyphenols --- phytophenols --- skin permeation --- chemotherapy --- radiotherapy --- active targeting --- passive targeting --- tumor --- immunoconjugate --- traditional liposome --- stealth liposome --- triggered release --- limitations of liposomes --- drug transfer --- in vitro release --- colloidal drug carriers --- lipid nanoparticles --- hydrogel beads --- cholesteryl nonanoate --- bovine serum albumin --- skin diseases --- lipid-based nanosystems --- cream --- ointment --- gel --- pH-sensitive --- liposome --- imidazole --- anticancer --- drug delivery --- multicellular spheroids --- dapagliflozin --- Box–Behnken design --- FTIR --- DSC --- XRD --- SEM --- AFM --- in vitro Franz diffusion cells --- lipid-based nanoparticles --- nanocarrier --- surface charge --- delivery systems --- chronic treatment --- mice --- anti-oxidant activity --- hepatoprotective effect --- phospholipid --- phytosomes --- Silymarin --- Colorectal Cancer --- Niosomes --- Oxaliplatin --- Paclitaxel --- d-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) --- therapeutic nucleic acids --- schizophrenia --- quetiapine fumarate --- glycerosomes --- central composite rotatable design --- bioavailability --- pharmacokinetic --- n/a --- Box-Behnken design