TY - BOOK ID - 96665831 TI - Flow chemistry in drug discovery AU - Alcazar, Jesus AU - Hoz, Antonio de la AU - Díaz-Ortiz, Angel PY - 2021 SN - 9783030855925 3030855929 3030855910 PB - Cham, Switzerland : Springer Nature Switzerland AG, DB - UniCat KW - Drug development. KW - Flow chemistry. KW - Chemical processes KW - Fluid dynamics KW - Development of drugs KW - Drugs KW - New drug development KW - Pharmacology KW - Pharmacy KW - Development KW - Pharmaceutical chemistry. KW - Chemistry, Medical and pharmaceutical KW - Chemistry, Pharmaceutical KW - Drug chemistry KW - Medical chemistry KW - Medicinal chemistry KW - Pharmacochemistry KW - Chemistry KW - Technology, Pharmaceutical. KW - Drug Discovery. KW - instrumentation. KW - Drug Prospecting KW - Discovery, Drug KW - Prospecting, Drug KW - High-Throughput Screening Assays KW - Bioprospecting KW - Pharmaceutic Technology KW - Pharmaceutical Technology KW - Pharmacy Technology KW - Technology, Pharmaceutic KW - Technology, Pharmacy KW - Drug Industry UR - https://www.unicat.be/uniCat?func=search&query=sysid:96665831 AB - This book reviews the challenges and opportunities posed by flow chemistry in drug discovery, and offers a handy reference tool for medicinal chemists interested in the synthesis of biologically active compounds. Prepared by expert contributors, the respective chapters cover not only fundamental methodologies and reactions, such as the application of catalysis, especially biocatalysis and organocatalysis; and non-conventional activation techniques, from photochemistry to electrochemistry; but also the development of new process windows, processes and reactions in drug synthesis. Particular attention is given to automatization and library synthesis, which are of great importance in the pharmaceutical industry. Readers will also find coverage on selected topics of general interest, such as how flow chemistry is contributing to drug discovery R&D in developing countries, and the green character of this enabling technology, for example in the production of raw materials for the pharmaceutical industry from waste. Given its scope, the book appeals to medicinal chemistry researchers working in academia and industry alike, as well as professionals involved in scale-up and drug development. ER -