TY - BOOK ID - 965361 TI - Antigen Processing and Presentation Protocols PY - 2001 SN - 0896037452 9786610820535 1280820535 1592590624 PB - Totowa, NJ : Humana Press : Imprint: Humana, DB - UniCat KW - Molecular biology KW - Antigen presenting cells KW - Antigens KW - HLA histocompatibility antigens KW - Major histocompatibility complex KW - Molecular immunology KW - HL-A histocompatibility antigens KW - HLA antigens KW - HLA transplantation antigens KW - Human leukocyte antigens KW - Transplantation antigens, Human KW - Histocompatibility antigens KW - Immunity KW - Immunoglobulins KW - Immune system KW - Immunology KW - Accessory cells KW - Immunologic accessory cells KW - Immunocompetent cells KW - Histocompatibility complex KW - MHC (Immunogenetics) KW - Immunogenetics KW - Molecular aspects KW - Immunology. KW - Immunobiology KW - Life sciences KW - Serology UR - https://www.unicat.be/uniCat?func=search&query=sysid:965361 AB - The processing and presentation of antigens by major histocompatibility complex (MHC) molecules is a crucial immunological phenomenon in infectious disease, malignancy, autoimmune disease, and transplantation. In Antigen Processing and Presentation Protocols, well-recognized and innovative experimentalists detail their cutting-edge methods for studying this complex process. Drawing on expertise from biochemistry, cell biology, and immunology, they describe step-by-step methods designed to question how MHC-binding peptides are generated, to test how peptides are delivered to MHC molecules, to analyze MHC peptide-binding patterns, and to assay the T cell response to the MHC/peptide complex. Each method is presented in sufficient detail to be readily reproducible and includes notes about potential pitfalls and tips on how to avoid failures. Emphasis is given those technical steps critical for experimental success that are often omitted from methods published in the primary literature. Eminently accessible and state-of-the-art, Antigen Processing and Presentation Protocols provides both new and experienced investigators with highly practical tools that will extend the questions that can be asked, and effectively be answered, concerning antigen processing/presentation. ER -