TY - BOOK ID - 947851 TI - Signaling networks and cell cycle control : the molecular basis of cancer and other diseases PY - 2000 VL - 5 SN - 089603710X 1468496956 9786610830800 1280830808 159259218X 0585310025 PB - Totowa, N.J. : Humana Press, DB - UniCat KW - Cell cycle. KW - Cellular control mechanisms. KW - Cellular signal transduction. KW - Pathology, Molecular. KW - Human histology. Human cytology KW - Human biochemistry KW - Cellular signal transduction KW - Cell cycle KW - Cellular control mechanisms KW - Pathology, Molecular KW - Transduction du signal cellulaire KW - Cycle cellulaire KW - ReĢgulation cellulaire KW - Pathologie moleĢculaire KW - Pharmacy. KW - Chemistry KW - Medicine KW - Drugs KW - Materia medica KW - Pharmacology KW - Cellular information transduction KW - Information transduction, Cellular KW - Signal transduction, Cellular KW - Bioenergetics KW - Information theory in biology UR - https://www.unicat.be/uniCat?func=search&query=sysid:947851 AB - The recent dramatic expansion of our knowledge about how cell surface receptors transmit signals to the nucleus, together with the identification of key signaling and cell-cycle-regulating molecules, has provided a major opportunity to search for novel targets for therapeutic intervention in many diseases. In Signaling Networks and Cell Cycle Control: The Molecular Basis of Cancer and Other Diseases, leading scientists summarize this knowledge and describe the effort to design and synthesize inhibiting molecules, as well as to evaluate their biochemical and biological activities. They review the relevant cell surface receptors, their ligands, and their downstream pathways. Also examined are the latest findings on the components of novel signaling networks controlling the activity of nuclear transcription factors and cell cycle regulatory molecules. Rich in cutting-edge insights and authoritative critical analysis, Signaling Networks and Cell Cycle Control: The Molecular Basis of Cancer and Other Diseases presents a wealth of information on the emerging principles of the field, as well as an invaluable guide for all experimental and clinical investigators of cell regulation and its rapidly emerging pharmacological opportunities today. ER -