TY - BOOK ID - 8656682 TI - Hepatitis C virus : from molecular virology to antiviral therapy PY - 2013 SN - 3642273394 364242936X 3642273408 PB - Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, DB - UniCat KW - Hepacivirus. KW - Hepatitis C virus. KW - Hepatitis C virus KW - Viral Vaccines KW - Hepatitis, Viral, Human KW - Flaviviridae KW - Hepatitis Viruses KW - Flaviviridae Infections KW - Viruses KW - Vaccines KW - RNA Viruses KW - Virus Diseases KW - RNA Virus Infections KW - Hepatitis KW - Vertebrate Viruses KW - Diseases KW - Organisms KW - Biological Products KW - Liver Diseases KW - Complex Mixtures KW - Digestive System Diseases KW - Chemicals and Drugs KW - Viral Hepatitis Vaccines KW - Hepacivirus KW - Hepatitis C KW - Biology KW - Health & Biological Sciences KW - Microbiology & Immunology KW - Immunology. KW - Medical virology. KW - Immunobiology KW - HCV (Hepatitis C virus) KW - Medicine. KW - Drug resistance. KW - Virology. KW - Hepatology. KW - Biomedicine. KW - Drug Resistance. KW - Life sciences KW - Serology KW - Gastroenterology KW - Microbiology KW - Resistance to drugs KW - Pharmacology KW - Clinical sciences KW - Medical profession KW - Human biology KW - Medical sciences KW - Pathology KW - Physicians KW - Medical microbiology KW - Virology KW - Virus diseases KW - Flaviviruses KW - Hepatitis viruses KW - Drug interactions. KW - Clinical medicine. KW - Interactions, Drug KW - Drugs KW - Medicine, Clinical KW - Medicine KW - Side effects UR - https://www.unicat.be/uniCat?func=search&query=sysid:8656682 AB - Hepatitis C virus (HCV), a major causative agent of chronic liver disease, is spread throughout the world and around 170 million people are persistently infected. In this volume, world-leading experts in the field of HCV research have compiled the most recent scientific advances to provide a comprehensive and very timely overview of the various facets of HCV. The book starts with a discussion of the possible origin of HCV and its spread among the human population. The focus of the subsequent chapters is on available cell culture and in vivo models before shifting to the molecular and cellular principles underlying the viral replication cycle. These chapters are complemented by insightful descriptions of the innate and adaptive immune responses to HCV as well as the virus-associated pathogenesis. Finally, the development of antiviral therapies, which is closely linked with progress in basic research, and the implementation of those therapies into present and future daily clinical practice are highlighted. ER -