TY - BOOK ID - 8434280 TI - Chemokine biology : basic research and clinical application. AU - Moser, Bernhard AU - Letts, Gordon L. AU - Neote, Kuldeep. PY - 2006 SN - 3764371951 9786610969883 1280969881 3764374373 PB - Basel ; Boston : Birkhauser, DB - UniCat KW - Chemokines. KW - Receptors, Chemokine. KW - Biology KW - Health & Biological Sciences KW - Microbiology & Immunology KW - Medicine. KW - Immunology. KW - Pharmacology. KW - Cell biology. KW - Biomedicine. KW - Pharmacology/Toxicology. KW - Cell Biology. KW - Cell biology KW - Cellular biology KW - Cells KW - Cytologists KW - Drug effects KW - Medical pharmacology KW - Medical sciences KW - Chemicals KW - Chemotherapy KW - Drugs KW - Pharmacy KW - Immunobiology KW - Life sciences KW - Serology KW - Clinical sciences KW - Medical profession KW - Human biology KW - Pathology KW - Physicians KW - Physiological effect KW - Toxicology. KW - Cytology. KW - Medicine KW - Pharmacology KW - Poisoning KW - Poisons KW - Toxicology UR - https://www.unicat.be/uniCat?func=search&query=sysid:8434280 AB - Chemokines play an important role in recruiting inflammatory cells into tissues in response to infection and inflammation. They also play an important role in coordinating the movement of T-cells, B-cells and dentritic cells, necessary to generate an immune response (response to injury, allergens, antigens, invading microorganisms). They selectively attract leukocytes to inflammatory foci, inducing both cell migration and activation. They are involved in various diseases, like atherosclerosis, lung and skin inflammation, multiple sclerosis, or HIV. Volume 2 of this two-volume set discusses the pathophysiology of chemokines. It is divided into two parts: a) chemokines in animal disease models, and b) chemokines as drug targets. Together with volume 1, which discusses the immunobiology of chemokines, both volumes give a comprehensive overview of chemokine biology. ER -