TY - BOOK ID - 8431705 TI - Pasteurella multocida : molecular biology, toxins and infection AU - Aktories, K. AU - Orth, Joachim H. C. AU - Adler, Ben. PY - 2012 SN - 3642438563 3642310168 9786613943255 3642310176 128363080X PB - New York : Springer, DB - UniCat KW - Molecular microbiology. KW - Pasteurella multocida. KW - Pathogenic bacteria. KW - Pasteurella multocida KW - Pathogenic bacteria KW - Molecular microbiology KW - Toxins, Biological KW - Pasteurella KW - Pasteurellaceae Infections KW - Pasteurellaceae KW - Gram-Negative Bacterial Infections KW - Biological Factors KW - Gram-Negative Facultatively Anaerobic Rods KW - Chemicals and Drugs KW - Gammaproteobacteria KW - Bacterial Infections KW - Bacterial Infections and Mycoses KW - Proteobacteria KW - Gram-Negative Bacteria KW - Diseases KW - Bacteria KW - Organisms KW - Bacterial Toxins KW - Pasteurella Infections KW - Health & Biological Sciences KW - Biology KW - Pharmacy, Therapeutics, & Pharmacology KW - Microbiology & Immunology KW - Molecular aspects. KW - Pasteurella septica KW - Medicine. KW - Medical microbiology. KW - Pharmacology. KW - Biomedicine. KW - Pharmacology/Toxicology. KW - Medical Microbiology. KW - Drug effects KW - Medical pharmacology KW - Medical sciences KW - Chemicals KW - Chemotherapy KW - Drugs KW - Pharmacy KW - Clinical sciences KW - Medical profession KW - Human biology KW - Life sciences KW - Pathology KW - Physicians KW - Physiological effect KW - Toxicology. KW - Microbiology. KW - Microbial biology KW - Microorganisms KW - Medicine KW - Pharmacology KW - Poisoning KW - Poisons KW - Toxicology UR - https://www.unicat.be/uniCat?func=search&query=sysid:8431705 AB - It is more than 125 years since Louis Pasteur identified as the causative agent of “choléra des poules” the bacterium that now bears his name. Since that time, Pasteurella multocida has been recognized as the causative agent of a wide range of infections in a wide range of animal species as well as in humans.  Indeed, the species name multocida could be literally translated as “multi-killer”. The term pasteurellosis is now widely applied to describe infections of mammals and birds caused by P. multocida.  It is therefore surprising that a detailed knowledge of the cellular and molecular basis for pathogenesis in pasteurellosis lags behind what has been elucidated for many other bacterial species.  In particular, the molecular basis for host predilection remains completely unknown.    This volume brings together contributions from experts in the field of Pasteurella research.  It covers areas such as comparative genomics, pathogenic mechanisms, bacterial proteomics, as well as a detailed description and analysis of Pasteurella multocida toxin and its interaction with host tissues, cells, immune system, and signalling pathways. . ER -