TY - BOOK ID - 8360794 TI - Stress-induced mutagenesis PY - 2013 SN - 1489994181 1461462797 1461462800 PB - New York : Springer, DB - UniCat KW - Environmentally induced diseases. KW - Epigenetics. KW - Mutagenesis. KW - Mutagenesis KW - Epigenetics KW - Genetic Processes KW - Genomics KW - Genetic Phenomena KW - Computational Biology KW - Biology KW - Phenomena and Processes KW - Biological Science Disciplines KW - Natural Science Disciplines KW - Disciplines and Occupations KW - Epigenomics KW - Medicine KW - Health & Biological Sciences KW - Pathology KW - Genetics KW - Medicine. KW - Human genetics. KW - Biochemistry. KW - Biomedicine. KW - Human Genetics. KW - Biochemistry, general. KW - Biomedicine general. KW - Mutation (Biology) KW - Radiogenetics KW - Teratogenesis KW - Clinical sciences KW - Medical profession KW - Human biology KW - Life sciences KW - Medical sciences KW - Physicians KW - Biological chemistry KW - Chemical composition of organisms KW - Organisms KW - Physiological chemistry KW - Chemistry KW - Heredity, Human KW - Physical anthropology KW - Composition KW - Health Workforce KW - Biomedicine, general. UR - https://www.unicat.be/uniCat?func=search&query=sysid:8360794 AB - The discoveries of stress-induced mutation and epigenetic inheritance have challenged the claim of independence between the evolutionary forces of mutation and selection. In “Stress-Induced Mutagenesis”, leading experts provide the key evidence for and the molecular details of stress-induced genetic and epigenetic mutation, integrating cross-disciplinary observations from a number of species and biological systems, including human. The observations have vast implications for evolutionary biology but also for human medicine. A comprehensive understanding of stress-induced mutagenesis and the processes underlying evolvability, will enable gains in the treatment and management of cancer, as well as other human disorders that result from damaged or unstable genomes. ER -