TY - BOOK ID - 8285075 TI - The hippo signaling pathway and cancer AU - Oren, Moshe. AU - Aylon, Yael. PY - 2013 SN - 1493901095 1461462193 1461462207 PB - New York : Springer, DB - UniCat KW - Cancer -- Genetic aspects. KW - Cancer -- Molecular aspects. KW - Cellular signal transduction. KW - Oncology. KW - Cancer KW - Neoplastic Processes KW - Peptides KW - Protein Kinases KW - Neoplasms KW - Phosphotransferases (Alcohol Group Acceptor) KW - Amino Acids, Peptides, and Proteins KW - Diseases KW - Chemicals and Drugs KW - Phosphotransferases KW - Transferases KW - Enzymes KW - Enzymes and Coenzymes KW - Intracellular Signaling Peptides and Proteins KW - Protein-Serine-Threonine Kinases KW - Cell Transformation, Neoplastic KW - Medicine KW - Health & Biological Sciences KW - Oncology KW - Genetic aspects KW - Genetic aspects. KW - Molecular aspects. KW - Cellular information transduction KW - Information transduction, Cellular KW - Signal transduction, Cellular KW - Cancer genetics KW - Medicine. KW - Cancer research. KW - Medical microbiology. KW - Cell biology. KW - Biomedicine. KW - Cancer Research. KW - Cell Biology. KW - Medical Microbiology. KW - Biomedicine general. KW - Bioenergetics KW - Cellular control mechanisms KW - Information theory in biology KW - Cancer genes KW - Cytology. KW - Microbiology. KW - Clinical sciences KW - Medical profession KW - Human biology KW - Life sciences KW - Medical sciences KW - Pathology KW - Physicians KW - Microbial biology KW - Biology KW - Microorganisms KW - Cell biology KW - Cellular biology KW - Cells KW - Cytologists KW - Tumors KW - Biomedicine, general. KW - Health Workforce KW - Cancer research UR - https://www.unicat.be/uniCat?func=search&query=sysid:8285075 AB - The Hippo signaling pathway is rapidly gaining recognition as an important player in organ size control and tumorgenesis. This volume presents virtually all aspects of tumor biology because members of the Hippo Pathway have been associated with numerous well-established cell signaling pathways, just to name a few; Rho, Wnt, TGFbeta and p53. Hippo signaling is not solely involved in regulating “classic” tumor characteristics such as cell proliferation, survival and growth, but is also diversely involved in cell-autonomous and non-cell-autonomous differentiation, migration and organ size control. With the multitude of signaling events mediated by the Hippo pathway and the vastly different functions that it plays, it is evident that these tumor suppressors are unique governors of cellular homeostasis. This timely volume gathers wide-ranging and burgeoning information on the Hippo pathway and its role in cancer into an accessible format of a single book.With the multitude of signaling events mediated by the Hippo pathway and the vastly different functions that it plays, it is evident that these tumor suppressors are unique governors of cellular homeostasis. This timely volume gathers wide-ranging and burgeoning information on the Hippo pathway and its role in cancer into an accessible format of a single book. ER -