TY - BOOK ID - 8211747 TI - Pancreatology : From Bench to Bedside AU - Iovanna, Juan. AU - Ismailov, Uktam. PY - 2009 SN - 3642001513 9786612924446 3642001521 1282924443 PB - Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, DB - UniCat KW - Pancreas -- Diseases. KW - Pancreas. KW - Pancreatic Diseases -- physiopathology -- Congresses. KW - Pancreatic Diseases -- therapy -- Congresses. KW - Pancreas KW - Pancreatic Diseases KW - Congresses KW - Digestive System Diseases KW - Publication Formats KW - Diseases KW - Publication Characteristics KW - Gastroenterology KW - Surgery - General and By Type KW - Surgery & Anesthesiology KW - Medicine KW - Health & Biological Sciences KW - Pancreatitis. KW - Diseases. KW - Inflammation KW - Medicine. KW - Internal medicine. KW - Gastroenterology. KW - Hepatology. KW - Surgery. KW - Surgical oncology. KW - Medicine & Public Health. KW - Internal Medicine. KW - Surgical Oncology. KW - Clinical medicine. KW - Cancer KW - Oncologic surgery KW - Oncological surgery KW - Surgical oncology KW - Medicine, Clinical KW - Medicine, Internal KW - Internal medicine KW - Digestive organs KW - Surgery, Primitive KW - Excision KW - Treatment KW - Gastroenterology . UR - https://www.unicat.be/uniCat?func=search&query=sysid:8211747 AB - 'Pancreatology: from Bench to Bedside' focusses on recent advances in pancreatic basic research, genetics of the pancreatic diseases and its surgical management. Basic research discusses the implication of pancreatic stress protein in acute pancreatitis and pancreatic cancer and their possible role as therapeutic targets. Also, very original results show the unexpected role of lipids as mediators during acute pancreatitis. Gene screening strategies allow the detection of the genes responsbile for gemcitabine resistance of pancreatic cancer cells . They lead to the selection of several target genes, in order to suppress the resistance of cells to gemcitabine treatment. The mechanism by which tetrahydrocannabinol is anti-tumoral in pancreatic cancer cells is presented and the use of THC as a promising new therapeutic agent is discussed. Genetic data are shown concerning hundreds of families with hereditary chronic pancreatitis and their possible role in the pathogenesis of the disease. Another very original study addresses the prevention and treatment of pancreatic diseases with diat. In clinical research, convincing data about the use of endoscopic sphicterotomy in the management of acute bilary pancreatitis is presented, based on the experience of a Center highly specialized in pancreatic diseases. ER -