TY - BOOK ID - 8211494 TI - Microarrays in diagnostics and biomarker development PY - 2012 SN - 3642282024 3642439764 3642282032 9786613697301 1280786914 PB - Heidelberg, Germany : Springer, DB - UniCat KW - Cytology. KW - DNA microarrays. KW - Medicine. KW - Protein microarrays. KW - DNA microarrays KW - Protein microarrays KW - Sequence Analysis KW - Molecular Probe Techniques KW - Investigative Techniques KW - Microarray Analysis KW - Nucleic Acid Hybridization KW - Genetic Techniques KW - Microchip Analytical Procedures KW - Analytical, Diagnostic and Therapeutic Techniques and Equipment KW - Chemistry Techniques, Analytical KW - Protein Array Analysis KW - Oligonucleotide Array Sequence Analysis KW - Clinical Laboratory Techniques KW - Human Anatomy & Physiology KW - Health & Biological Sciences KW - Animal Biochemistry KW - Biomedical Engineering KW - Biochemical markers. KW - Biologic markers KW - Biological markers KW - Biomarkers KW - Markers, Biochemical KW - DNA biochips KW - Microarrays, DNA KW - Microarrays. KW - Cell biology. KW - Biomedicine. KW - Cell Biology. KW - Biochemistry KW - Indicators (Biology) KW - Biochips KW - Immobilized nucleic acids KW - Cell biology KW - Cellular biology KW - Biology KW - Cells KW - Cytologists UR - https://www.unicat.be/uniCat?func=search&query=sysid:8211494 AB - Microarray technology has made strong progress over the past decade, and there have also been significant changes in application areas, from nucleic acids to proteomics and from research to clinical applications. This book provides a comprehensive overview of microarrays in diagnostics and biomarker development, covering DNA, peptide, protein and tissue arrays. The focus is on entities that are in actual clinical use, or quite close, and on recent developments, such as peptide and aptamer arrays. A further topic is the miniaturisation towards “nanoarrays”, which is expected to have great potential in clinical applications. Relevant issues of bioinformatics and statistical analysis of array data are discussed in detail, as well as the barriers to the commercialisation of array-based tests and the vexing IP issues involved. Thus, the book should be very useful tor active array users as well as to newcomers seeking to make the best choice between different technologies. ER -