TY - BOOK ID - 8136493 TI - CRISPR-Cas systems : RNA-mediated adaptive immunity in bacteria and archaea AU - Barrangou, Rodolphe. AU - Oost, John van der. PY - 2013 SN - 3642346561 3642429297 364234657X 1283935422 PB - New York : Springer, DB - UniCat KW - Molecular biology. KW - Molecular genetics. KW - Bacterial genetics KW - Biological Evolution KW - Biology KW - Immunity KW - RNA KW - Organisms KW - Genetic Processes KW - Immune System Phenomena KW - Biological Science Disciplines KW - Nucleic Acids KW - Nucleic Acids, Nucleotides, and Nucleosides KW - Genetic Phenomena KW - Natural Science Disciplines KW - Phenomena and Processes KW - Chemicals and Drugs KW - Disciplines and Occupations KW - Evolution, Molecular KW - Genetics KW - Bacteria KW - RNA, Archaeal KW - Archaea KW - RNA, Bacterial KW - Adaptive Immunity KW - Health & Biological Sciences KW - Microbiology & Immunology KW - Immunity. KW - CRISPR (Genetics) KW - Clustered Regularly Interspaced Short Palindromic Repeats (Genetics) KW - Life sciences. KW - Medical microbiology. KW - Microbiology. KW - Microbial genetics. KW - Microbial genomics. KW - Life Sciences. KW - Microbial Genetics and Genomics. KW - Medical Microbiology. KW - Genomics KW - Microbial genetics KW - Microorganisms KW - Microbiology KW - Microbial biology KW - Biosciences KW - Sciences, Life KW - Science KW - Immunology UR - https://www.unicat.be/uniCat?func=search&query=sysid:8136493 AB - CRISPR-Cas is a recently discovered defense system which protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR-Cas immune systems has been identified in at least half of the available prokaryotic genomes. On-going biochemical and functional analyses have resulted in substantial insight into the functions and possible applications of these fascinating systems, although many secrets remain to be uncovered. In this book, experts summarize the state of the artĀ of this exciting field. ER -