TY - BOOK ID - 8134576 TI - Autophagy at the Cell, Tissue and Organismal Level AU - Karanasios, Eleftherios. AU - Ktistakis, Nicholas T. PY - 2016 SN - 3319331434 3319331450 PB - Cham : Springer International Publishing : Imprint: Springer, DB - UniCat KW - Cytology KW - Biology KW - Health & Biological Sciences KW - Cell death. KW - Cell degeneration KW - Cells KW - Death (Biology) KW - Cytology. KW - Immunology. KW - Biochemistry. KW - Cell Biology. KW - Animal Biochemistry. KW - Biological chemistry KW - Chemical composition of organisms KW - Organisms KW - Physiological chemistry KW - Chemistry KW - Medical sciences KW - Immunobiology KW - Life sciences KW - Serology KW - Cell biology KW - Cellular biology KW - Cytologists KW - Composition KW - Cell biology. UR - https://www.unicat.be/uniCat?func=search&query=sysid:8134576 AB - This book provides an expert summary of autophagy, a relatively new but rapidly expanding field of biomedical science with important implications in health and disease. After a historical review ranging up to the identification of autophagy genes in mammals, the authors discuss the signaling pathways that regulate autophagy, the mechanism of autophagosome formation and the physiological roles of autophagy in development, ageing, neurodegeneration, immune function and cell differentiation. A comprehensive list of useful antibodies for studying autophagy compiled as a community effort is included at the end. The book is intended for newcomers to the field, as well as more experienced researchers looking for a condensed but comprehensive introduction to the physiological function and regulation of the autophagic pathway in mammalian organisms. ER -