TY - BOOK ID - 80732303 TI - Emerging Chagas Disease. AU - Teixeira, António AU - Vinaud, Marina AU - Castro, Ana Maria PY - 2011 SN - 1608050416 9781608050413 PB - Sharjah Bentham Science Publishers DB - UniCat KW - Chagas' disease. KW - American trypanosomiasis KW - Barbiero fever KW - Cruz-Chagas disease KW - South American trypanosomiasis KW - Trypanosomiasis UR - https://www.unicat.be/uniCat?func=search&query=sysid:80732303 AB - The book focuses on a global problem challenging the health systems. Trypanosoma cruzi infections are transmitted by cone-nosed triatomine bugs, by blood transfusion and congenitally from mothers to their offspring. The American Trypanosomiasis affects 20 million people; among them a significant parcel (< 1/3) will develop Chagas disease in the heart and digestive tract, where the immune system effector cells destroy target host cells. Genotype modifications resulting from transfer of minicircle sequence kDNA from the parasite into the host ́s genome may explain the autoimmune pathogenesis. ER -