TY - BOOK ID - 8062169 TI - Oocyte Biology in Fertility Preservation PY - 2013 SN - 1461482135 1461482143 PB - New York, NY : Springer New York : Imprint: Springer, DB - UniCat KW - Fertilization. KW - Human reproduction. KW - Medicine. KW - Ovum KW - Infertility, Female KW - Fertility, Human KW - Human reproduction KW - Infertility KW - Investigative Techniques KW - Adnexa Uteri KW - Preservation, Biological KW - Therapeutic Uses KW - Diseases KW - Surgical Procedures, Operative KW - Pharmacologic Actions KW - Genital Diseases, Female KW - Specimen Handling KW - Genitalia, Female KW - Analytical, Diagnostic and Therapeutic Techniques and Equipment KW - Genitalia KW - Female Urogenital Diseases KW - Laboratory Techniques and Procedures KW - Chemical Actions and Uses KW - Urogenital System KW - Chemicals and Drugs KW - Female Urogenital Diseases and Pregnancy Complications KW - Diagnosis KW - Anatomy KW - Transplantation KW - Ovary KW - Neoplasms KW - Cryopreservation KW - Methods KW - Antineoplastic Agents KW - Medicine KW - Human Anatomy & Physiology KW - Health & Biological Sciences KW - Physiology KW - Gynecology & Obstetrics KW - Prevention KW - Endocrine aspects KW - Molecular aspects KW - Reproductive health. KW - Fertility. KW - Fecundity KW - Human reproductive health KW - Human reproductive medicine KW - Reproductive medicine KW - Health aspects KW - Molecular biology. KW - Reproductive medicine. KW - Cell biology. KW - Medicine & Public Health. KW - Reproductive Medicine. KW - Cell Biology. KW - Molecular Medicine. KW - Cell biology KW - Cellular biology KW - Biology KW - Cells KW - Cytologists KW - Health KW - Molecular biochemistry KW - Molecular biophysics KW - Biochemistry KW - Biophysics KW - Biomolecules KW - Systems biology KW - Clinical sciences KW - Medical profession KW - Human biology KW - Life sciences KW - Medical sciences KW - Pathology KW - Physicians KW - Reproduction KW - Infertility in animals KW - Cytology. KW - Health Workforce UR - https://www.unicat.be/uniCat?func=search&query=sysid:8062169 AB - Fertility preservation has become one of the most important and fast growing fields of reproductive medicine. Although there are several strategies for fertility preservation in female, most of them are still considered experimental. It is important to perfect the existing technologies, but also developing new strategies should be actively sought. The future development of fertility preservation strategies should be based on the sound scientific knowledge and principles. One of the main objectives of fertility preservation in females is prevention of oocyte depletion. The mechanisms of oocyte loss and survival in the ovary are complex, which include genetic control both in germ cells and in somatic cells, DNA damage and repair mechanism, apoptosis and autophagy, and other poorly understood molecular mechanisms. To develop clinically effective and safe strategies for fertility preservation, it is essential to know and understand the fundamentals of oocyte and ovarian biology at the molecular level. Thus, the purpose of this edition is to review the current progress in research related to molecular and genetic control of oocyte development that can be applied to fertility preservation. The main topics that are discussed in this publication include molecular signaling mechanisms of oocyte activation and loss, genomic integrity of oocytes, and epigenetics. . ER -