TY - BOOK ID - 7988690 TI - Alcohol and cancer AU - Zakhari, Samir. AU - Vasiliou, Vasilis. AU - Guo, Q. Max. PY - 2011 SN - 1489986375 1461400392 9786613351753 1283351757 1461400406 PB - New York : Springer, DB - UniCat KW - Alcohol KW - Digestive organs KW - Alcoholism KW - Substance-Related Disorders KW - Publication Formats KW - Diseases KW - Publication Characteristics KW - Mental Disorders KW - Psychiatry and Psychology KW - Neoplasms KW - Alcohol-Related Disorders KW - Congresses KW - Medicine KW - Health & Biological Sciences KW - Oncology KW - Carcinogenicity KW - Etiology KW - Cancer KW - Complications KW - Alcoholic liver diseases. KW - Carcinogenicity. KW - Etiology. KW - Complications. KW - Alcoholic liver damage KW - Alcoholic liver injury KW - Complications and sequelae KW - Medicine. KW - Cancer research. KW - Pharmacology. KW - Biomedicine. KW - Cancer Research. KW - Pharmacology/Toxicology. KW - Liver KW - Oncology. KW - Toxicology. KW - Chemicals KW - Pharmacology KW - Poisoning KW - Poisons KW - Tumors KW - Toxicology KW - Drug effects KW - Medical pharmacology KW - Medical sciences KW - Chemotherapy KW - Drugs KW - Pharmacy KW - Cancer research KW - Physiological effect UR - https://www.unicat.be/uniCat?func=search&query=sysid:7988690 AB - The World Health Organization has identified chronic alcohol consumption as one of the top ten risk factors for worldwide burden of disease. The International Agency for Research on Cancer has identified alcohol as carcinogenic to humans, including cancers of the upper aerodigestive tract, colon, liver and breast. Alcohol’s actions may be direct e.g. effects on retinoic acid and one-carbon metabolism, or indirect, through metabolites such as acetaldehyde and reactive oxygen species or through various signaling pathways that influence cell cycle and apoptosis that may contribute to carcinogenesis. This volume reviews the state of the art in alcohol-related cancer research in ten chapters. ER -