TY - BOOK ID - 7988689 TI - Ribosomes : structure, function, and dynamics AU - Rodnina, Marina V. AU - Wintermeyer, Wolfgang. AU - Green, Rachel. PY - 2011 SN - 3709102146 3709102154 PB - Vienna : Springer, DB - UniCat KW - Ribosomes -- Congresses. KW - Ribosomes -- Structure -- Congresses. KW - Ribosomes. KW - RNA, Ribosomal. KW - Ribosomes KW - Proteins KW - RNA KW - Metabolic Phenomena KW - Organelles KW - Phenomena and Processes KW - Nucleic Acids KW - Cytoplasmic Structures KW - Amino Acids, Peptides, and Proteins KW - Chemicals and Drugs KW - Cytoplasm KW - Nucleic Acids, Nucleotides, and Nucleosides KW - Intracellular Space KW - Cellular Structures KW - Cells KW - Anatomy KW - Metabolism KW - RNA, Ribosomal KW - Ribosomal Proteins KW - Human Anatomy & Physiology KW - Biology KW - Health & Biological Sciences KW - Cytology KW - Physiology KW - Structure KW - Ribonucleoprotein particles KW - Medicine. KW - Gene expression. KW - Nucleic acids. KW - Biophysics. KW - Biological physics. KW - Biomedicine. KW - Gene Expression. KW - Nucleic Acid Chemistry. KW - Biophysics and Biological Physics. KW - Cell organelles KW - Microsomes KW - Nucleoproteins KW - Protoplasm KW - Biological and Medical Physics, Biophysics. KW - Polynucleotides KW - Biomolecules KW - Genes KW - Genetic regulation KW - Expression KW - Biological physics KW - Medical sciences KW - Physics KW - Molecular genetics. KW - Biomaterials. KW - Molecular Genetics. KW - Nucleic Acid. KW - Genetics KW - Molecular biology UR - https://www.unicat.be/uniCat?func=search&query=sysid:7988689 AB - The ribosome is a macromolecular machine that synthesizes proteins with a high degree of speed and accuracy. Our present understanding of its structure, function and dynamics is the result of six decades of research. This book collects over 40 articles based on the talks presented at the 2010 Ribosome Meeting, held in Orvieto, Italy, covering all facets of the structure and function of the ribosome. New high-resolution crystal structures of functional ribosome complexes and cryo-EM structures of translating ribosomes are presented, while partial reactions of translation are examined in structural and mechanistic detail, featuring translocation as a most dynamic process. Mechanisms of initiation, both in bacterial and eukaryotic systems, translation termination, and novel details of the functions of the respective factors are described. Structure and interactions of the nascent peptide within, and emerging from, the ribosomal peptide exit tunnel are addressed in several articles. Structural and single-molecule studies reveal a picture of the ribosome exhibiting the energy landscape of a processive Brownian machine. The collection provides up-to-date reviews which will serve as a source of essential information for years to come. ER -