TY - BOOK ID - 7988566 TI - Calorie restriction, aging and longevity PY - 2010 SN - 9048185564 9048185556 9786612924712 9400791151 1282924710 PB - Dordrecht ; London : Springer, DB - UniCat KW - Aging -- Nutritional aspects. KW - Longevity -- Nutritional aspects. KW - Low-calorie diet. KW - Older people -- Nutrition. KW - Longevity KW - Aging KW - Older people KW - Low-calorie diet KW - Biological Science Disciplines KW - Energy Intake KW - Physiological Phenomena KW - Growth and Development KW - Diet Therapy KW - Caloric Restriction KW - Physiology KW - Diet KW - Phenomena and Processes KW - Natural Science Disciplines KW - Nutrition Therapy KW - Physiological Processes KW - Nutritional Physiological Phenomena KW - Disciplines and Occupations KW - Therapeutics KW - Analytical, Diagnostic and Therapeutic Techniques and Equipment KW - Public Health KW - Human Anatomy & Physiology KW - Public Health - General KW - Health & Biological Sciences KW - Nutritional aspects KW - Nutrition KW - Nutritional aspects. KW - Nutrition. KW - Caloric restriction KW - Calorie-restricted diet KW - Calorie restriction KW - Diet, Low-calorie KW - Medicine. KW - Human physiology. KW - Geriatrics. KW - Oxidative stress. KW - Biomedicine. KW - Human Physiology. KW - Geriatrics/Gerontology. KW - Oxidative Stress. KW - Reducing diets KW - Cytology. KW - Cell biology KW - Cellular biology KW - Biology KW - Cells KW - Cytologists KW - Medicine KW - Gerontology KW - Human biology KW - Medical sciences KW - Human body KW - Diseases KW - Health and hygiene KW - Oxidation-reduction reaction KW - Stress (Physiology) UR - https://www.unicat.be/uniCat?func=search&query=sysid:7988566 AB - Food or calorie restriction has been shown in many short-lived animals and the rhesus monkey to prolong life-span. Life-long nutrition studies are not possible in humans because of their long survival. Studies over two to six years in healthy adult humans have, however, shown that a 20% reduction in food or calorie intake slows many indices of normal and disease-related aging. Thus, it is widely believed that long-term reduction in calorie or food intake will delay the onset of age-related diseases such as heart disease, diabetes and cancer, and so prolong life. Over the last 20 or more years there has been a progressive rise in food intake in many countries of the world, accompanied by a rising incidence of obesity. Thus our increasing food and calorie intake has been linked to the rising incidence of cardiovascular disease and diabetes in early adult life. It is accepted that overeating, accompanied by reduced physical exercise, will lead to more age-related diseases and shortening of life-span. The answer is to reduce our calorie intake, improve our diet, and exercise more. But calorie restriction is extremely difficult to maintain for long periods. How then can we solve this problem? Edited by a team of highly distinguished academics, this book provides the latest information on the beneficial effects of calorie restriction on health and life-span. This book brings us closer to an understanding at the molecular, cellular and whole organism level of the way forward. ER -