TY - BOOK ID - 7986662 TI - Systems biology and biotechnology of Escherichia coli PY - 2009 SN - 9048181186 1402093934 9786612047855 128204785X 1402093942 PB - Dordrecht : Springer Netherlands, DB - UniCat KW - Escherichia coli. KW - Systems biology. KW - Escherichia coli KW - Systems biology KW - Systems Biology KW - Escherichia KW - Computational Biology KW - Biology KW - Enterobacteriaceae KW - Biological Science Disciplines KW - Gram-Negative Facultatively Anaerobic Rods KW - Gammaproteobacteria KW - Natural Science Disciplines KW - Proteobacteria KW - Gram-Negative Bacteria KW - Bacteria KW - Disciplines and Occupations KW - Organisms KW - Biochemistry KW - Biology - General KW - Microbiology & Immunology KW - Chemistry KW - Health & Biological Sciences KW - Physical Sciences & Mathematics KW - Biochemistry. KW - Biotechnology. KW - Life sciences. KW - Microbial genetics. KW - Microorganisms KW - Biosciences KW - Sciences, Life KW - Biological chemistry KW - Chemical composition of organisms KW - Physiological chemistry KW - E. coli (Bacterium) KW - Genetics KW - Composition KW - Microbiology. KW - Microbial genomics. KW - Life Sciences. KW - Biochemistry, general. KW - Microbial Genetics and Genomics. KW - Applied Microbiology. KW - Microbiology KW - Science KW - Chemical engineering KW - Genetic engineering KW - Medical sciences KW - Genomics KW - Microbial genetics KW - Microbial biology UR - https://www.unicat.be/uniCat?func=search&query=sysid:7986662 AB - Systems biology is changing the way biological systems are studied by allowing us to examine the cell and organism as a whole. Systems biotechnology allows optimal design and development of upstream to downstream bioprocesses by taking a systems-approach. E. Coli has been a model organism for almost all biological and biotechnological studies. This book brings together for the first time the state-of-the-art reviews by the world-leading experts on systems biology and biotechnological applications of E. coli. The topics covered include genomics and functional genomics, resources for systems biology, network analysis, genome-scale metabolic reconstruction, modelling and simulation, dynamic modelling and simulation, systems-level analysis of evolution, plasmids and expression systems, protein synthesis, production and export, engineering the central metabolism, synthetic biology, and systems metabolic engineering of E. coli. This book provides readers with guidance on how a complex biological system can be studied using E. Coli as a model organism. It also presents how to perform synthetic biology and systems metabolic engineering studies on E. Coli with successful examples, the approaches of which can be extended to other organisms. This book will be a complete resource for anyone interested in systems biology and biotechnology. ER -