TY - BOOK ID - 7839810 TI - Iron uptake in bacteria with emphasis on e. coli and pseudomonas PY - 2013 SN - 9400760876 9400760884 1299407552 PB - Dordrecht ; New York : Springer, DB - UniCat KW - Pseudomonas aeruginosa infections --Congresses. KW - Biology KW - Health & Biological Sciences KW - Microbiology & Immunology KW - Escherichia coli. KW - Pseudomonas. KW - E. coli (Bacterium) KW - Chemistry. KW - Molecular biology. KW - Microbiology. KW - Biochemistry. KW - Applied Microbiology. KW - Biochemistry, general. KW - Molecular Medicine. KW - Pseudomonadaceae KW - Escherichia KW - Medicine. KW - Clinical sciences KW - Medical profession KW - Human biology KW - Life sciences KW - Medical sciences KW - Pathology KW - Physicians KW - Biological chemistry KW - Chemical composition of organisms KW - Organisms KW - Physiological chemistry KW - Chemistry KW - Microbial biology KW - Microorganisms KW - Composition KW - Health Workforce KW - Molecular biochemistry KW - Molecular biophysics KW - Biochemistry KW - Biophysics KW - Biomolecules KW - Systems biology KW - Iron KW - Biotechnology. KW - Physiological effect. UR - https://www.unicat.be/uniCat?func=search&query=sysid:7839810 AB - Iron is essential for the growth of most bacteria because it serves as a cofactor for vital enzymes and for the components of the electron transport chain. Moreover, Iron plays an important role in bacterial pathogenicity; in fact, the iron transport systems in bacteria works as target for designing novel antibiotics. Because iron is not soluble under aerobic conditions, bacteria have had to find ways to overcome iron deficiency. One of them is producing an iron-chelating small organic molecule called siderophore. Indeed, most bacteria and fungi produce structurally and chemically diverse siderophores which are transported back to the cytoplasm using complex energy dependent transport systems. Escherichia coli and Pseudomonas were the first ones to be tested; however, nowadays iron transport systems have been investigated in many other bacteria. Iron Uptake in Bacteria with Emphasis on E. coli and Pseudomonas reviews the recent advancements in the field of iron transport systems in bacteria. Chapter 1 is dedicated to Dr. Dick van der Helm’s contribution to the field of siderophore biology. It then describes and discusses the structural advances in the components and the mechanism of siderophore mediated iron transport systems in E.coli. Chapter 2 details the variety of iron transport and iron regulatory systems of both gram negative and gram positive bacteria. Finally, chapter 3 describes the iron transport systems of Pseudomonas. This book is aimed at researchers in the fields of iron metabolism in multiple organisms, and to those who are interested in studying iron transport systems of bacteria. It appeals also to scientists researching structure and function relationship of proteins. ER -