TY - BOOK ID - 7838150 TI - Morphine and metastasis PY - 2013 SN - 9400792964 9400756771 940075678X 128391087X PB - New York : Springer, DB - UniCat KW - Morphine -- Therapeutic use. KW - Morphine. KW - Opioids. KW - Metastasis KW - Growth Substances KW - Therapeutics KW - Morphinans KW - Biological Science Disciplines KW - Neoplastic Processes KW - Neoplasms KW - Phenanthrenes KW - Analytical, Diagnostic and Therapeutic Techniques and Equipment KW - Pathologic Processes KW - Opiate Alkaloids KW - Natural Science Disciplines KW - Heterocyclic Compounds with 4 or More Rings KW - Heterocyclic Compounds, Bridged-Ring KW - Physiological Effects of Drugs KW - Heterocyclic Compounds KW - Pathological Conditions, Signs and Symptoms KW - Disciplines and Occupations KW - Diseases KW - Pharmacologic Actions KW - Polycyclic Hydrocarbons, Aromatic KW - Alkaloids KW - Chemicals and Drugs KW - Chemical Actions and Uses KW - Polycyclic Compounds KW - Morphine KW - Growth Inhibitors KW - Pharmacology KW - Neoplasm Metastasis KW - Drug Therapy KW - Medicine KW - Health & Biological Sciences KW - Oncology KW - Metastasis. KW - Cancer KW - Chemotherapy. KW - Cancer metastasis KW - Dissemination of cancer KW - Metastases KW - Metastatic cancer KW - Neoplasm metastasis KW - Spread of cancer KW - Tumor dissemination KW - Tumor metastasis KW - Tumor spread KW - Morphia KW - Dissemination KW - Medicine. KW - Pharmacy. KW - Cancer research. KW - Pharmacology. KW - Oncology. KW - Pain medicine. KW - Biomedicine. KW - Cancer Research. KW - Pharmacology/Toxicology. KW - Pain Medicine. KW - Antineoplastic agents KW - Pathology KW - Cancer invasiveness KW - Cancer of unknown primary origin KW - Narcotics KW - Opium KW - Treatment KW - Toxicology. KW - Oncology . KW - Tumors KW - Chemicals KW - Poisoning KW - Poisons KW - Chemistry KW - Drugs KW - Materia medica KW - Toxicology KW - Algiatry KW - Drug effects KW - Medical pharmacology KW - Medical sciences KW - Chemotherapy KW - Pharmacy KW - Cancer research KW - Physiological effect UR - https://www.unicat.be/uniCat?func=search&query=sysid:7838150 AB - The possibility that morphine and other opioids may modulate tumour growth and metastasis has been researched for many years. The recent past has seen multiple clinical studies attempting to document whether limiting the perioperative use of morphine is beneficial for cancer surgery patients. Furthermore, a lot of exciting new data has been generated in vitro, but also in preclinical and clinical studies, that indirectly shed light on the effect of opioids on cancer. This book combines chapters written by qualified experts around the world whose research encompasses the effect of morphine or other opioids on tumour growth and metastasis. This includes clinicians, researchers working on animal models and studying the effect of morphine on tumours, and most importantly the mechanism for this effect, and lastly cell biologists. Current investigations and cross talk between basic science and clinical trials will refine our understanding of the multiple levels of actions of morphine and other opioids on tumour growth and metastasis, and result in improved guidelines for patient care. This book will be of interest to clinicians, especially those dealing with cancer patients and their pain management, as well as students, teachers and scientists in the fields of anaesthesiology, oncology, tumour biology, immunology, opioid pharmacology. ER -