TY - BOOK ID - 77945406 TI - MIF : most interesting factor PY - 2007 SN - 128192895X 9786611928957 9812775919 9789812775917 PB - Hackensack, NJ : World Scientific, DB - UniCat KW - Macrophage migration inhibitory factor. KW - Macrophages. KW - Histiocytes KW - Mononuclear phagocytes KW - Antigen presenting cells KW - Connective tissue cells KW - Killer cells KW - Phagocytes KW - Reticulo-endothelial system KW - Inhibition factor, Macrophage migration KW - Inhibitory factor, Macrophage migration KW - Macrophage migration inhibition factor KW - MIF (Macrophage migration inhibitory factor) KW - Migration inhibition factor, Macrophage KW - Migration inhibitory factor, Macrophage KW - Lymphokines UR - https://www.unicat.be/uniCat?func=search&query=sysid:77945406 AB - In recent years, researchers have identified a pivotal, upstream role for macrophage migration inhibitory factor (MIF) in the innate immune response. This pioneering book describes this renaissance of knowledge in the biology of MIF. Topics covered include MIF's molecular mechanism of action, its counterregulatory action on the immunosuppressive properties of glucocorticoids, its role in the production of proinflammatory mediators as shown in cell-based and animal studies; and its central role in human inflammation. Human genetic studies have identified allelic forms of the MIF gene, and high- ER -