TY - BOOK ID - 77920178 TI - Modern concepts in angiogenesis AU - Simons, Michael. AU - Rubanyi, Gabor M. PY - 2007 SN - 1281867543 9786611867546 1860949452 9781860949456 9781281867544 9781860947636 1860947638 6611867546 PB - London : Hackensack, NJ : Imperial College Press ; Distributed by World Scientific Pub., DB - UniCat KW - Neovascularization. KW - Vascular endothelial growth factors. KW - Vascular endothelial growth factors KW - Neovascularization inhibitors. KW - Angiogenesis inhibitors KW - Tumor angiogenesis inhibitors KW - Antineoplastic agents KW - Angiogenic factors KW - Angiogenic proteins KW - Endothelial growth factors, Vascular KW - VEGFs (Proteins) KW - Growth factors KW - Blood-vessels KW - Therapeutic use. KW - Growth UR - https://www.unicat.be/uniCat?func=search&query=sysid:77920178 AB - "This volume addresses current emerging concepts in the field of angiogenesis, including important angiogenesis modifiers which are essential in combination with growth factors (VEGF and FGF) for the physiological process and also for therapeutic applications. It covers many of the lesser discussed areas including blood vessel growth guidance (interactions with CNS) as well as emerging practical applications of these concepts. The book comprises in-depth reviews by leading experts in several major areas: recent basic science discoveries about angiogenesis modifiers (semaphorins, ephrins and nitric oxide, for which the Nobel Prize was awarded); arterial guidance; clinical applications of new angiogenic factors (HGF, HIF and eNOS); and basic and clinical advancement of anti-angiogenic molecules for the treatment of cancer and macular degeneration (tyrosine kinase inhibitors and NO). These topics, especially their unique combination presented in this volume, are not found in any other current books on angiogenesis. This makes the book a must-read for readers both interested and actively involved in the most recent advances in basic principles and clinical applications of angiogenesis." ER -