TY - BOOK ID - 77892107 TI - Free energy relationships in organic and bio-organic chemistry PY - 2003 SN - 1847550924 9781847550927 0854046763 9780854046768 9781788018302 1788018303 PB - Cambridge Royal Society of Chemistry DB - UniCat KW - Linear free energy relationship. KW - Correlation analysis (Chemistry) KW - Correlation equation (Chemistry) KW - Free energy relationship, Linear KW - Chemical reaction, Conditions and laws of KW - Gibbs' free energy KW - Linear free energy relationship KW - 541.124 KW - 541.124 Chemical dynamics in general. Reaction mechanism in general KW - 541.124 Limits of reactions KW - Chemical dynamics in general. Reaction mechanism in general KW - Limits of reactions UR - https://www.unicat.be/uniCat?func=search&query=sysid:77892107 AB - Introducing the application of free energy correlations to elucidating the mechanisms of organic and bio-organic reactions, this book provides a new and illuminating way of approaching a potentially complex topic. The idea of how free energy correlations derive from polar substituent change is introduced, and common pitfalls encountered in the application of free energy relationships are described, along with the use of these anomalies in mechanistic studies. The concept of effective charge is described in detail, with examples of its application. Throughout, worked answers are provided for th ER -