TY - BOOK ID - 7691742 TI - Sex and gender differences in pharmacology PY - 2012 VL - v. 214 SN - 01712004 SN - 3642428029 3642307256 3642307264 128369753X PB - New York : Springer, DB - UniCat KW - Drug discrimination (Pharmacology). KW - Drug therapy. KW - Pharmacological phenomena. KW - Pharmacology -- Sex differences. KW - Sex factors. KW - Drug discrimination (Pharmacology) KW - Epidemiologic Factors KW - Therapeutics KW - Physiological Phenomena KW - Analytical, Diagnostic and Therapeutic Techniques and Equipment KW - Phenomena and Processes KW - Quality of Health Care KW - Public Health KW - Environment and Public Health KW - Health Care Quality, Access, and Evaluation KW - Health Care KW - Sex Factors KW - Drug Therapy KW - Pharmacological Phenomena KW - Health & Biological Sciences KW - Pharmacy, Therapeutics, & Pharmacology KW - Pharmacology KW - Medical care KW - Sex differences. KW - Delivery of health care KW - Delivery of medical care KW - Health care KW - Health care delivery KW - Health services KW - Healthcare KW - Medical and health care industry KW - Medical services KW - Personal health services KW - Drug effects KW - Medical pharmacology KW - Medicine. KW - Molecular biology. KW - Pharmacology. KW - Pharmaceutical technology. KW - Biomedicine. KW - Pharmacology/Toxicology. KW - Molecular Medicine. KW - Pharmaceutical Sciences/Technology. KW - Public health KW - Medical sciences KW - Chemicals KW - Chemotherapy KW - Drugs KW - Pharmacy KW - Physiological effect KW - Toxicology. KW - Pharmaceutical laboratory techniques KW - Pharmaceutical laboratory technology KW - Technology, Pharmaceutical KW - Technology KW - Clinical sciences KW - Medical profession KW - Human biology KW - Life sciences KW - Pathology KW - Physicians KW - Medicine KW - Poisoning KW - Poisons KW - Toxicology KW - Health Workforce KW - Molecular biochemistry KW - Molecular biophysics KW - Biochemistry KW - Biophysics KW - Biomolecules KW - Systems biology UR - https://www.unicat.be/uniCat?func=search&query=sysid:7691742 AB - This is the very first book to deal with sex and gender differences in drug therapy - an increasingly recognized medical need. It starts with an overview on S/G in clinical syndromes and a documentation of the medical and socioeconomic damage caused by gender specific adverse drug effects. Part I covers S/G differences in pharmacokinetics. Researchers will be satisfied by the detailed discussion of the mechanisms of S/G differences in drug effects that represents cutting edge science and includes interaction of drugs with sex hormones, genomic and epigenetic mechanisms. It also covers S/G in drug development, in animal models and clinical development and S/G in drug prescriptions. Part II targets S/G differences in drug effects in cardiovascular, pulmonary, CNS, neuromuscular, neuropsychiatric and metabolic diseases, in cancer, inflammation, and rheumatic diseases, in bacterial and retroviral infections, thrombosis, embolism. New drugs will be discussed. ER -