TY - BOOK ID - 7617265 TI - Prostate Cancer Prevention AU - Cuzick, Jack. AU - Thorat, Mangesh A. PY - 2014 SN - 3642451942 3642451950 PB - Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, DB - UniCat KW - Cancer. KW - Prostate -- Cancer -- Popular works. KW - Testis -- Cancer. KW - Prostate KW - Genital Neoplasms, Male KW - Risk KW - Investigative Techniques KW - Psychology, Social KW - Prostatic Diseases KW - Drug Therapy KW - Biological Factors KW - Analytical, Diagnostic and Therapeutic Techniques and Equipment KW - Urogenital Neoplasms KW - Probability KW - Genital Diseases, Male KW - Behavior and Behavior Mechanisms KW - Chemicals and Drugs KW - Therapeutics KW - Male Urogenital Diseases KW - Psychiatry and Psychology KW - Statistics as Topic KW - Neoplasms by Site KW - Epidemiologic Methods KW - Diseases KW - Neoplasms KW - Biological Markers KW - Chemoprevention KW - Prostatic Neoplasms KW - Risk Assessment KW - Diet KW - Risk Factors KW - Life Style KW - Medicine KW - Health & Biological Sciences KW - Oncology KW - Prevention KW - Cancer KW - Prevention. KW - Medicine. KW - Cancer research. KW - Oncology. KW - Urology. KW - Medicine & Public Health. KW - Cancer Research. KW - Genitourinary organs KW - Tumors KW - Cancer research KW - Clinical sciences KW - Medical profession KW - Human biology KW - Life sciences KW - Medical sciences KW - Pathology KW - Physicians KW - Oncology  . UR - https://www.unicat.be/uniCat?func=search&query=sysid:7617265 AB - Prostate cancer is by far the most common cancer in men and the second leading cause of death due to cancer. It comprises a mixed group of tumours displaying varying clinical behaviour: while some have a very aggressive course, others are rather indolent. Prevention of prostate cancer and discrimination between aggressive and indolent forms are important clinical goals, and the acquisition of significant new evidence on means of achieving these aims makes this book particularly timely.   A wide range of topics are covered by leading authorities in the field. The biology and natural history of prostate cancer are reviewed, and the role of lifestyle and dietary factors, assessed. Detailed attention is paid to risk prediction biomarkers and to the role of novel high-throughput nucleic acid-based technologies in improving risk prediction and thereby allowing tailored approaches to cancer prevention. Potential means of chemoprevention of prostate cancer are also reviewed in depth, covering the very positive new data on the impact of aspirin as well as evidence regarding 5α-reductase inhibitors, DFMO, and lycopene. Guidance is provided on the differentiation of aggressive from indolent disease, and the policy and research implications of recent findings are examined. This book will be of interest to both clinicians and researchers. ER -