TY - BOOK ID - 7615373 TI - Liver metastases PY - 2009 SN - 1849966842 1846289467 1846289475 PB - London : Springer, DB - UniCat KW - Colorectal Neoplasms -- Pathology. KW - Liver metastasis -- Treatment. KW - Liver Neoplasms -- Secondary. KW - Liver Neoplasms -- Therapy. KW - Liver metastasis KW - Colorectal Neoplasms KW - Liver Neoplasms KW - Pathology KW - Intestinal Neoplasms KW - Liver Diseases KW - Rectal Diseases KW - Digestive System Neoplasms KW - Colonic Diseases KW - Medicine KW - Health Occupations KW - Intestinal Diseases KW - Gastrointestinal Neoplasms KW - Digestive System Diseases KW - Neoplasms by Site KW - Diseases KW - Neoplasms KW - Gastrointestinal Diseases KW - Disciplines and Occupations KW - Oncology KW - Health & Biological Sciences KW - Treatment KW - Liver KW - Treatment. KW - Cancer. KW - Hepatocellular carcinoma KW - Hepatic metastasis KW - Medicine. KW - Radiology. KW - Oncology. KW - Proctology. KW - Surgery. KW - Medicine & Public Health. KW - Imaging / Radiology. KW - Metastasis KW - Cancer KW - Oncology . KW - Endocrinology. KW - Radiology, Medical. KW - Internal medicine KW - Hormones KW - Tumors KW - Surgery, Primitive KW - Clinical radiology KW - Radiology, Medical KW - Radiology (Medicine) KW - Medical physics KW - Radiological physics KW - Physics KW - Radiation KW - Gastroenterology UR - https://www.unicat.be/uniCat?func=search&query=sysid:7615373 AB - The management of colorectal liver metastases has evolved rapidly over the last decade with the introduction of newer and effective chemotherapies and a redefinition for cure. These range from the philosophical (including the greater awareness of treatment with curative intent), through the practical (more aggressive definition of respectability for cure and the use of more effective chemotherapies for both palliation and as adjuncts to surgery), to the futuristic use of biological strategies (including monoclonal antibodies and gene therapies) and lastly to the pragmatic but equally important issues of health economics (who is going to foot the bill for these increasingly expensive treatment strategies). Liver metastases addresses the contemporary multidisciplinary management of liver metastases. Throughout the text, experience from the paradigms of colorectal cancer metastases treatment strategies are used to point to new directions in the management of liver metastases from other cancers. This book overviews current understanding of the biology of liver metastases, and reviews current methods of detection and diagnosis. Chapters offer objective and systematic reviews of each of the current major treatment modalities: surgical resection; destructive therapies; chemotherapy (systemic and regional); whether there is a role for radiotherapy; biological therapies (including hormone treatment antibodies and gene therapy); and lastly the decision-making strategies that must be employed for successful multidisciplinary management. Featuring state-of-the-art reviews, key points, treatment algorithms and clear, concise illustrations this book provides the ultimate companion to anyone interested or working in the area of liver disease. This book will appeal to consultant and trainee surgeons in general surgery, hepatobiliary surgery, upper GI surgery, colorectal surgery; consultant and trainee medical and clinical oncologists with an interest in liver tumours; and consultant and trainee radiologists with an interest in liver disease. ER -