TY - BOOK ID - 7615077 TI - Cholesterol binding and cholesterol transport proteins : structure and function in health and disease PY - 2010 SN - 9048186218 9786612924750 9048186226 1282924753 PB - Dordrecht ; New York : Springer, DB - UniCat KW - Carrier proteins. KW - Cholesterol -- Metabolism. KW - Cholesterol KW - Carrier proteins KW - Sterols KW - Proteins KW - Cholestenes KW - Carrier Proteins KW - Membrane Lipids KW - Amino Acids, Peptides, and Proteins KW - Cholestanes KW - Lipids KW - Steroids KW - Chemicals and Drugs KW - Polycyclic Compounds KW - Human Anatomy & Physiology KW - Chemistry KW - Biology KW - Biology - General KW - Animal Biochemistry KW - Cytology KW - Biochemistry KW - Health & Biological Sciences KW - Physical Sciences & Mathematics KW - Metabolism KW - Cholesterol. KW - Metabolism. KW - Binding proteins KW - Transport proteins KW - Cholesterin KW - Life sciences. KW - Biochemistry. KW - Proteins. KW - Lipids. KW - Apoptosis. KW - Life Sciences. KW - Biochemistry, general. KW - Lipidology. KW - Protein Science. KW - Animal Biochemistry. KW - Biological transport KW - Protein binding KW - Isopentenoids KW - Low-cholesterol diet UR - https://www.unicat.be/uniCat?func=search&query=sysid:7615077 AB - Knowledge of cholesterol and its interaction with protein molecules is of fundamental importance in both animal and human biology. This book contains 22 chapters, dealing in depth with structural and functional aspects of the currently known and extremely diverse unrelated families of cholesterol-binding and cholesterol transport proteins. By drawing together this range of topics the Editor has attempted to correlate this broad field of study for the first time. Technical aspects are given considerable emphasis, particularly in relation cholesterol reporter molecules and to the isolation and study of membrane cholesterol- and sphingomyelin-rich "raft" domains. Cell biological, biochemical and clinical topics are included in this book, which serve to emphasize the acknowledged and important benefits to be gained from the study of cholesterol and cholesterol-binding proteins within the biomedical sciences and the involvement of cholesterol in several clinical disorders. It is hoped that by presenting this topic in this integrated manner that an appreciation of the fact that there is much more that needs to be taken into account, studied and understood than the widely discussed "bad and good cholesterol" associated, respectively, with the low- and high-density lipoproteins, LDL and HDL. ER -