TY - BOOK ID - 7608816 TI - Complement methods and protocols PY - 2000 SN - 0896036545 9786610821648 1280821647 159259056X 1617371165 PB - Totowa : Humana Press, DB - UniCat KW - Complement (Immunology) -- Laboratory manuals. KW - Electronic books. -- local. KW - Immunology. KW - Complement (Immunology) KW - Immunoproteins KW - Blood Proteins KW - Proteins KW - Amino Acids, Peptides, and Proteins KW - Chemicals and Drugs KW - Complement System Proteins KW - Biology KW - Health & Biological Sciences KW - Microbiology & Immunology KW - Immunobiology KW - Life sciences KW - Serology KW - Alexin KW - Complements (Immunity) KW - Blood proteins KW - Complement system proteins KW - analysis UR - https://www.unicat.be/uniCat?func=search&query=sysid:7608816 AB - Although the complement system-a vital part of the body's defense against bacteria-was discovered more than a century ago, its study has undergone a renaissance with the identification of its regulatory molecules and the realization that these molecules can be used therapeutically. In Complement Methods and Protocols, B. Paul Morgan and a team of expert laboratorians present a comprehensive set of readily reproducible methods to study this critical system. These cutting-edge techniques are suitable both for the basic scientist interested in understanding complement's mechanisms of activation and for the clinical scientist wishing to quantify its activation, and range from the purification of its components to generating complement-deficient mice by gene deletion. Additional techniques presented include procedures for the analysis of complement function, for the study of its regulators, for detection of its activation in vivo, and for the identification of its autoantibodies. Comprehensive and cutting-edge, Complement Methods and Protocols offers today's basic and clinical investigators powerful tools for the analysis of the role of complement in human pathophysiology and disease, as well as its therapeutic regulation. ER -