TY - BOOK ID - 67957554 TI - MicroRNAs PY - 2008 SN - 9780521865982 0521865980 9780511541766 9780521118552 9780511457180 0511457189 0511541767 1107178886 1281944513 9786611944513 0511455887 0511454074 0511453167 0511455119 PB - Cambridge New York Cambridge University Press DB - UniCat KW - RNA. KW - Nucleic acids. KW - Polynucleotides KW - Biomolecules KW - Ribonucleic acid KW - Ribose nucleic acid KW - Nucleic acids KW - Ribose UR - https://www.unicat.be/uniCat?func=search&query=sysid:67957554 AB - MicroRNAs (miRNAs) are RNA molecules, conserved by evolution, that regulate gene expressions and their discovery has revolutionised both basic biomedical research and drug discovery. Expression levels of MiRNAs have been found to vary between tissues and with developmental stages and hence evaluation of the global expression of miRNAs potentially provides opportunities to identify regulatory points for many different biological processes. This wide-ranging 2007 reference work, written by leading experts from both academia and industry, will be an invaluable resource for all those wishing to use miRNA techniques in their own research, from graduate students, post-docs and researchers in academia to those working in R&D in biotechnology and pharmaceutical companies who need to understand this emerging technology. From the discovery of miRNAs and their functions to their detection and role in disease biology, this volume uniquely integrates the basic science with industry application towards drug validation, diagnostic and therapeutic development. ER -