TY - BOOK ID - 65497393 TI - Vaccination strategies against highly variable pathogens AU - Hangartner, Lars. AU - Burton, Dennis R. PY - 2020 SN - 3030580040 3030580032 PB - Springer International Publishing DB - UniCat KW - Vaccines. KW - Infectious diseases. KW - Virology. KW - Immunology. KW - Human physiology. KW - Vaccine. KW - Infectious Diseases. KW - Human Physiology. KW - Human biology KW - Medical sciences KW - Physiology KW - Human body KW - Immunobiology KW - Life sciences KW - Serology KW - Microbiology KW - Biologicals KW - Infectious & contagious diseases. KW - Medical microbiology & virology. UR - https://www.unicat.be/uniCat?func=search&query=sysid:65497393 AB - Vaccines against antigenically stable pathogens, or pathogens that only exist in a limited number of serotypes, have been very successful in the past and have drastically decreased the incidence and lethality of many diseases. However, when it comes to highly variable pathogens or viruses that exist in multiple serotypes, the traditional methods for vaccine development have reached their limits. This volume highlights the development of vaccines against such challenging pathogens. Novel approaches for immunogen design, including structure-guided vaccine development and vaccines targeting glycans, as well as adjuvants and animal models used for testing possible vaccine candidates are outlined and discussed in detail. Given its scope, the book will appeal to scientists in the fields of infectious diseases, microbiology and medicine. . ER -