TY - BOOK ID - 64931132 TI - Pharmaceutical Crystals AU - Uekusa, Hidehiro AU - Yonemochi, Etsuo PY - 2020 SN - 3039287133 3039287125 PB - MDPI - Multidisciplinary Digital Publishing Institute DB - UniCat KW - crystal structure analysis KW - n/a KW - famotidine KW - solution crystallization KW - salt optimization KW - structure determination from powder diffraction data KW - Hirshfeld surface analysis KW - DFT KW - molecular docking study KW - melting diagram KW - dehydration KW - hygroscopicity KW - HBV KW - Benzodioxole KW - pharmaceutical crystals KW - 4-b]indol-4-one KW - pyrimidin-4(3H)-one KW - liquid assisted grinding KW - HOMO-LUMO KW - dissolution KW - cocrystal formation KW - Raman spectroscopy KW - carbamazepine KW - hydrogen bonding KW - 3 KW - ondansetron KW - physicochemical properties KW - solubility KW - succinic acid KW - cocrystal KW - adefovir dipivoxil KW - hepatitis B KW - polymorphs KW - hydrogen-bond-acceptance ability KW - DFT study KW - Nitrofurantoin–4-dimethylaminopyridine (NF-DMAP) salt KW - photostability KW - on-line monitoring KW - 5-dihydro-4H-pyrimido[5 KW - Imidazole KW - Semicarbazone KW - crystal habit KW - Crystal structure KW - solvent-mediated polymorphic transformation KW - ticagrelor KW - hydrate KW - pharmaceutical cocrystal KW - malonic acid KW - 1H-indole KW - reactivity descriptors KW - famoxadone KW - crystal structure KW - dicarboxylic acid KW - hydrogen bond KW - saccharin KW - Nitrofurantoin-4-dimethylaminopyridine (NF-DMAP) salt UR - https://www.unicat.be/uniCat?func=search&query=sysid:64931132 AB - The crystalline state is the most commonly used essential solid active pharmaceutical ingredient (API). The characterization of pharmaceutical crystals encompasses many scientific disciplines, but the core is crystal structure analysis, which reveals the molecular structure of essential pharmaceutical compounds. Crystal structure analysis provides important structural information related to the API's wide range of physicochemical properties, such as solubility, stability, tablet performance, color, and hygroscopicity. This book entitled “Pharmaceutical Crystals"" focuses on the relationship between crystal structure and physicochemical properties. In particular, the new crystal structure of pharmaceutical compounds involving multi-component crystals, such as co-crystals, salts, and hydrates, and polymorph crystals are reported. Such crystal structures were investigated in the latest studies that combined morphology, spectroscopic, theoretical calculation, and thermal analysis with crystallographic study. This book highlights the importance of crystal structure information in many areas of pharmaceutical science and presents current trends in the structure–property study of pharmaceutical crystals. The Guest Editors of this book hope the readers enjoy a wide variety of recent studies on Pharmaceutical Crystals. ER -