TY - BOOK ID - 64913640 TI - Coronary Artery Disease: Therapeutics and Drug Discovery PY - 2020 SN - 981152517X 9811525161 PB - Singapore : Springer Singapore : Imprint: Springer, DB - UniCat KW - Pharmacology. KW - Cardiology. KW - Pharmacotherapy. KW - Cardiac surgery. KW - Pharmacology/Toxicology. KW - Cardiac Surgery. KW - Cardiac surgery KW - Heart KW - Open-heart surgery KW - Drug therapy KW - Pharmacotherapy KW - Therapeutics KW - Drugs KW - Pharmacology KW - Internal medicine KW - Drug effects KW - Medical pharmacology KW - Medical sciences KW - Chemicals KW - Chemotherapy KW - Pharmacy KW - Diseases KW - Surgery KW - Physiological effect KW - Coronary heart disease KW - Treatment. KW - Malalties coronàries KW - Quimioteràpia KW - Cirurgia cardíaca KW - Cirurgia del cor KW - Cirurgia cardiovascular KW - Cateterisme cardíac KW - Derivació cardiopulmonar KW - Trasplantament cardíac KW - Anestèsia en cardiologia KW - Farmacoteràpia KW - Immunoquimioteràpia KW - Terapèutica medicamentosa KW - Terapèutica per agents químics (Medicina) KW - Tractament amb medicaments KW - Tractament per agents químics (Medicina) KW - Us terapèutic dels medicaments KW - Terapèutica KW - Administració de medicaments KW - Antibiòtics KW - Diürètics KW - Fotoquimioteràpia KW - Pirogens KW - Psicofarmacologia KW - Prescripció de medicaments KW - Quimioteràpia del càncer KW - Utilització de medicaments KW - Farmacologia KW - Medicaments KW - Arterioesclerosi coronària KW - Cardiopatia isquèmica KW - Coronariopaties KW - Isquèmia miocardíaca KW - Malalties de les artèries coronàries KW - Malalties cardiovasculars KW - Angina de pit KW - Infart de miocardi KW - Chemotherapy. KW - Surgery. UR - https://www.unicat.be/uniCat?func=search&query=sysid:64913640 AB - This book provides an overview of the etiology of coronary artery disease and focuses on the main therapies and drug interventions currently available. It highlights drug pharmacology and therapeutic challenges, with a special emphasis on the underlying principles of available therapeutics and the on-going development of drugs for coronary artery disease. The book is divided into eight chapters, the first of which describes the classical mechanism of coronary artery disease and its clinical presentations. Chapter 2 lists the principles of and related evidence on the prevention and treatment of coronary artery disease. This includes diet and lifestyle management, and guidelines for the treatment of acute coronary syndrome and stable coronary artery disease. In turn, Chapter 3 describes revascularization treatments, covering percutaneous coronary interventions, coronary artery bypass grafts and thrombolysis. This chapter also addresses the main therapeutic challenges. The following chapters provide an overview of three major categories of coronary artery disease drugs, which target thrombosis (Chapter 4), lipid metabolism (Chapter 5), and hypertension (Chapter 6). Heart failure constitutes the major health burden in the late stage of coronary artery disease; accordingly, current heart failure therapeutics and related drug pharmacology are described in Chapter 7. In closing, Chapter 8 provides a summary of on-going clinical trials for coronary artery disease drug development and discusses a number of promising areas in which intensive research into new therapeutics is being pursued. Given its scope, the book will be of interest to clinicians, medical students and research scientists, as well as to pharmaceutical professionals who are seeking new therapies and drugs for coronary artery disease and related disorders. ER -