TY - BOOK ID - 64660972 TI - Cancer Epigenetics for Precision Medicine : Methods and Protocols AU - Dumitrescu, Ramona G. AU - Verma, Mukesh. PY - 2018 SN - 1493987518 149398750X PB - New York, NY : Springer New York : Imprint: Humana, DB - UniCat KW - Oncology. KW - Cancer Research. KW - Tumors UR - https://www.unicat.be/uniCat?func=search&query=sysid:64660972 AB - This volume discusses certain epigenetic changes recognized in early carcinogenic lesions and different tumors, as well as factors that alter the epigenome and epigenetic profile such as diet, alcohol, immunity, circadian rhythm, and more. The chapters in this book further delve into this field and cover topics such as epigenome-based precision medicine in lung cancer; interplay between genetic and epigenetic changes in breast cancer subtypes; genetic regulation of PDCD1 gene in cancer immunology; and pyrosequencing methylation analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and authoritative, Cancer Epigenetics for Precision Medicine: Methods and Protocols is a valuable resource to help researchers and scientists identify these specific biomarkers and work towards the prevention, diagnosis, and prognosis of different cancers in the future. ER -