TY - BOOK ID - 63978032 TI - Neuroproteomics : Methods and Protocols AU - Ottens, Andrew K. AU - Wang, Kevin K.W. PY - 2009 SN - 1597455628 1934115843 PB - Totowa, NJ : Humana Press : Imprint: Humana, DB - UniCat KW - Neurology. KW - Neurobiology. KW - Neurosciences. KW - Human physiology. KW - Cell physiology. KW - Human Physiology. KW - Cell Physiology. KW - Neurosciences KW - Cell function KW - Cytology KW - Physiology KW - Medicine KW - Nervous system KW - Neuropsychiatry KW - Neural sciences KW - Neurological sciences KW - Neuroscience KW - Medical sciences KW - Human biology KW - Human body KW - Diseases UR - https://www.unicat.be/uniCat?func=search&query=sysid:63978032 AB - With the development of polypeptide ionization processes for mass spectrometry and the rapid processing of large-scale datasets with bioinformatics, researchers now have the tools necessary to propel neuroproteomics research to new levels. In Neuroproteomics: Methods and Protocols, experts in the neurological and analytical sciences present experimental details for applying proteomics to the study of the central nervous system (CNS) and its dysfunction through trauma and disease. Divided into four convenient sections, this collection covers CNS animal models used for neuroproteomics research, methods for separating and analyzing discrete subcomponents of the neuroproteome, large-scale approaches for CNS proteome characterization and quantification, as well as methods that evaluate biofluids and translate neuroproteomic results into clinical platforms. As a volume in the highly successful Methods in Molecular Biology™ series, chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Neuroproteomics: Methods and Protocols includes the clear "how-to" information needed to critically assess what can be accomplished in the field and how to best perform and evaluate neuroproteomic experiments in one’s own research. ER -